{"id":"W4296230878","doi":"10.1158/1557-3265.sarcomas22-a026","title":"Abstract A026: PROX1 transcription factor regulates rhabdomyosarcoma growth, myogenic properties and therapeutic targets","year":2022,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Sarcoma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Rhabdomyosarcoma; Gene silencing; Cancer research; Transcription factor; Fibroblast growth factor receptor; Medicine; Cancer; Cell growth; Soft tissue sarcoma; Internal medicine; Biology; Fibroblast growth factor; Receptor; Sarcoma; Pathology; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001886375,0.0003806529,0.0003186769,0.000366112,0.0003706349,0.0005384214,0.0003078778,0.0005231308,0.01035399],"category_scores_gemma":[0.0001005295,0.0001667111,0.0002786716,0.0002865504,0.000252999,0.0004058472,0.000349103,0.0006085372,0.003141782],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005033888,"about_ca_system_score_gemma":0.0005178662,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007425839,"about_ca_topic_score_gemma":0.0009496992,"domain_scores_codex":[0.9998865,0.000009071078,0.000008855827,0.00002879134,0.00004778174,0.00001900485],"domain_scores_gemma":[0.999945,0.000004664697,0.00001233901,0.000003048035,0.00001517897,0.00001974126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005124905,0.00004961214,0.0005546345,0.0004488091,0.00001152505,0.0002195442,0.00003612966,0.0001409679,0.9787233,0.001212971,0.004205089,0.01388487],"study_design_scores_gemma":[0.0001392642,0.0006055201,0.01671711,0.00006121879,0.00006972063,0.001315851,0.0001472312,0.001411235,0.8741835,0.0005776801,0.1047413,0.00003043938],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8240778,0.07317728,0.0229266,0.008484547,0.004046692,0.0004827747,0.01299612,0.002261,0.05154719],"genre_scores_gemma":[0.844007,0.0246918,0.008312899,0.0007747927,0.0004896828,0.0002365821,0.009332509,0.0002796639,0.1118751],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01035399,"threshold_uncertainty_score":0.03463751,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3131991688682432,"score_gpt":0.4529131557970671,"score_spread":0.139713986928824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}