{"id":"W4296234769","doi":"10.1016/j.bbrep.2022.101344","title":"A real-time measurement system for gene expression rhythms from deep tissues of freely moving mice under light-dark conditions","year":2022,"lang":"en","type":"article","venue":"Biochemistry and Biophysics Reports","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Japan Society for the Promotion of Science; Japan Society for the Promotion of Science London; Canadian Society of Nephrology","keywords":"PER1; CLOCK; Circadian rhythm; Suprachiasmatic nucleus; Rhythm; Gene expression; Biology; Oscillating gene; Light effects on circadian rhythm; Circadian clock; Gene; Cell biology; Neuroscience; Internal medicine; Genetics; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001299043,0.001030988,0.0007620807,0.001366142,0.000645565,0.0007276568,0.000678919,0.0007841027,0.003387988],"category_scores_gemma":[0.0006344716,0.0005156238,0.0004612443,0.001004703,0.0006375384,0.0007519485,0.000469139,0.001606727,0.001273593],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005897012,"about_ca_system_score_gemma":0.0008035378,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005436316,"about_ca_topic_score_gemma":0.001685735,"domain_scores_codex":[0.9986066,0.0001803304,0.00007020863,0.0006946579,0.0003452683,0.0001029744],"domain_scores_gemma":[0.9993393,0.0001133659,0.0001373634,0.00009338256,0.000176885,0.0001397328],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000121329,0.00003185767,0.0005721982,0.00004158949,0.00001053302,0.00001502579,0.00005384133,0.00005428986,0.9949115,0.0001680439,0.0002458485,0.003774044],"study_design_scores_gemma":[0.00008259484,0.0006815121,0.01115401,0.00002224796,0.0001095882,0.0003071731,0.00005455194,0.006964818,0.9712711,0.000324325,0.00895657,0.00007161382],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.2436374,0.001820831,0.7382415,0.0004638592,0.0005867615,0.0004559393,0.004970628,0.006235821,0.003587299],"genre_scores_gemma":[0.3009354,0.001379765,0.6742527,0.0009824422,0.000210201,0.00438306,0.00584298,0.0008569295,0.0111564],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003387988,"threshold_uncertainty_score":0.01133394,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02027318637643531,"score_gpt":0.236489430433585,"score_spread":0.2162162440571497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}