{"id":"W4296234769","doi":"10.1016/j.bbrep.2022.101344","title":"A real-time measurement system for gene expression rhythms from deep tissues of freely moving mice under light-dark conditions","year":2022,"lang":"en","type":"article","venue":"Biochemistry and Biophysics Reports","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Japan Society for the Promotion of Science; Japan Society for the Promotion of Science London; Canadian Society of Nephrology","keywords":"PER1; CLOCK; Circadian rhythm; Suprachiasmatic nucleus; Rhythm; Gene expression; Biology; Oscillating gene; Light effects on circadian rhythm; Circadian clock; Gene; Cell biology; Neuroscience; Internal medicine; Genetics; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001591262,0.0001579717,0.0002280746,0.00002546565,0.0003464031,0.00002828521,0.00008132939,0.00006452687,0.0000212616],"category_scores_gemma":[0.00005473299,0.0001590822,0.00009358474,0.0001267864,0.0000616647,0.00005940381,0.0001137149,0.00008354295,0.000001176164],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000105929,"about_ca_system_score_gemma":0.00009735686,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000419224,"about_ca_topic_score_gemma":2.274761e-7,"domain_scores_codex":[0.9984862,0.000037502,0.0003515007,0.0005259391,0.0004053871,0.0001935125],"domain_scores_gemma":[0.9990271,0.00006122023,0.0003764598,0.0003531621,0.00007841566,0.0001036542],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002475996,0.00007521215,0.00003837145,0.0001109169,0.00001226388,0.0001162484,0.0001265627,0.00003249006,0.9990542,0.0001249675,0.0002246298,0.00005940437],"study_design_scores_gemma":[0.0002041967,0.00003385281,0.0001067868,0.00009344215,0.00004002242,0.0002698368,0.0002589344,0.000113556,0.9980242,0.0003611203,0.0003095978,0.0001844192],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976576,0.0003905684,0.0002256703,0.00005343324,0.0002459162,0.0002742378,0.0003197882,0.00006445999,0.0007683249],"genre_scores_gemma":[0.9989622,0.00001778843,0.0003678141,0.00002082434,0.0001781177,0.0001105321,0.00007885056,0.00001942795,0.0002444624],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001304582,"threshold_uncertainty_score":0.6487184,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02027318637643531,"score_gpt":0.236489430433585,"score_spread":0.2162162440571497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}