{"id":"W4296311689","doi":"10.1016/j.isci.2022.105095","title":"MTFR2 shapes a barrier of immune microenvironment in hepatocellular carcinoma","year":2022,"lang":"en","type":"article","venue":"iScience","topic":"Ferroptosis and cancer prognosis","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Key Research and Development Program of China; Natural Science Foundation of Hunan Province; National Natural Science Foundation of China","keywords":"Hepatocellular carcinoma; Immunotherapy; Immune system; Tumor microenvironment; Regulator; Cancer research; Cancer immunotherapy; Cancer; Immunity; Immunology; Biology; Medicine; Internal medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004152639,0.0002635741,0.0004201729,0.0007180558,0.0003863268,0.0005240706,0.0001776572,0.0002736124,0.0007170707],"category_scores_gemma":[0.0006410573,0.00009940891,0.0003836658,0.0006266796,0.0001580091,0.0003752971,0.0003993029,0.0002859053,0.000237568],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004545009,"about_ca_system_score_gemma":0.000333486,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003647113,"about_ca_topic_score_gemma":0.005813631,"domain_scores_codex":[0.9997739,0.00003430046,0.0000178363,0.00007451735,0.00005429137,0.00004502497],"domain_scores_gemma":[0.9997628,0.00003968113,0.00008963387,0.00002632706,0.00004939122,0.00003219031],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001824607,0.0001498058,0.6063139,0.0006778344,0.0004741902,0.0008927083,0.000317578,0.005769827,0.3355287,0.001020851,0.008315511,0.0387145],"study_design_scores_gemma":[0.00007478418,0.0002762109,0.8675539,0.0001043377,0.0004121733,0.001866006,0.000659233,0.02154143,0.08119848,0.001621994,0.02463362,0.00005779507],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893954,0.001894737,0.001249167,0.0002414371,0.00001613222,0.00001048191,0.006167933,0.0001220828,0.000902568],"genre_scores_gemma":[0.9843091,0.0004726133,0.001326419,0.0001014785,0.0000105346,0.00001364886,0.01327966,0.00002081846,0.0004657657],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003647113,"threshold_uncertainty_score":0.007251799,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01592308711783628,"score_gpt":0.231890627615091,"score_spread":0.2159675404972548,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}