{"id":"W4296311689","doi":"10.1016/j.isci.2022.105095","title":"MTFR2 shapes a barrier of immune microenvironment in hepatocellular carcinoma","year":2022,"lang":"en","type":"article","venue":"iScience","topic":"Ferroptosis and cancer prognosis","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Key Research and Development Program of China; Natural Science Foundation of Hunan Province; National Natural Science Foundation of China","keywords":"Hepatocellular carcinoma; Immunotherapy; Immune system; Tumor microenvironment; Regulator; Cancer research; Cancer immunotherapy; Cancer; Immunity; Immunology; Biology; Medicine; Internal medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002782647,0.0000655,0.0001617978,0.00008215333,0.00007228682,0.000004130681,0.0001633157,0.00001285574,0.001412719],"category_scores_gemma":[0.00001204289,0.00005948115,0.00005639223,0.0002994628,0.0001249191,0.00003753744,0.0001715335,0.000109298,0.000005837537],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001182674,"about_ca_system_score_gemma":0.00007793149,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002249337,"about_ca_topic_score_gemma":0.000003062361,"domain_scores_codex":[0.9990245,0.00002852201,0.0002086262,0.0002169314,0.0003420405,0.0001794105],"domain_scores_gemma":[0.9997037,0.000009783084,0.00005485041,0.000172381,0.000008950026,0.00005035342],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00003590071,0.0001570381,0.5693261,0.00002420615,0.00000312851,0.00002898829,0.0008193238,0.00005412781,0.4258116,0.00004385489,0.00008551396,0.003610194],"study_design_scores_gemma":[0.0008042909,0.0005131025,0.8197829,0.00003404022,0.00001855122,0.00003254026,0.00113165,0.003656321,0.1659892,0.00002514377,0.007895434,0.0001168411],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946388,0.003758984,0.00001503904,0.0005475601,0.00005731851,0.0001998383,0.000008753766,0.000005931261,0.0007677929],"genre_scores_gemma":[0.9991128,0.00004838816,0.0001747402,0.0002607405,0.0000100697,0.00007894827,0.000001658033,0.000006206914,0.0003064064],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2598224,"threshold_uncertainty_score":0.9995001,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01592308711783628,"score_gpt":0.231890627615091,"score_spread":0.2159675404972548,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}