{"id":"W4296312339","doi":"10.3390/biomimetics7030136","title":"Effects of rmBMP-7 on Osteoblastic Cells Grown on a Nanostructured Titanium Surface","year":2022,"lang":"en","type":"article","venue":"Biomimetics","topic":"Bone Tissue Engineering Materials","field":"Engineering","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Canadian Institutes of Health Research; Réseau de Recherche en Santé Buccodentaire et Osseuse; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"RUNX2; Osteoblast; Chemistry; Titanium; In situ; Cell culture; Alkaline phosphatase; Cellular differentiation; Cell growth; Cell biology; Bone morphogenetic protein 2; In vitro; Molecular biology; Biophysics; Biology; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001487158,0.0003324746,0.0003502016,0.000156634,0.0000898777,0.0002239741,0.0002078688,0.0003464162,0.000538618],"category_scores_gemma":[0.0001827879,0.0001821972,0.0002410362,0.0001382236,0.0001319066,0.000124327,0.0001775024,0.0003386992,0.0001549072],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001652207,"about_ca_system_score_gemma":0.0001149996,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006936259,"about_ca_topic_score_gemma":0.001600384,"domain_scores_codex":[0.9998035,0.00001843607,0.00001580697,0.00003036807,0.0001030159,0.00002895172],"domain_scores_gemma":[0.9999121,0.00002527556,0.00001743256,0.00001092899,0.00002298631,0.00001122583],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002863491,0.000007967249,0.00006311999,0.00003084448,0.000002708317,0.0000367837,0.000008511169,0.00005339725,0.9993005,0.000008130232,0.00000560912,0.0004538202],"study_design_scores_gemma":[0.000006063724,0.0001963449,0.00199944,0.000004907468,0.00001234136,0.00006895266,0.00002904291,0.0005075678,0.9965186,0.000008999561,0.0006438742,0.000003823005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960681,0.001626254,0.001067861,0.00003323066,0.00004259347,0.00002007672,0.0001095297,0.0000171689,0.001015157],"genre_scores_gemma":[0.9941021,0.001002803,0.003180331,0.00005097238,0.00001565051,0.00003436825,0.0001761621,0.00001113434,0.001426577],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006936259,"threshold_uncertainty_score":0.001801848,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003625393900866453,"score_gpt":0.169005345398396,"score_spread":0.1653799514975295,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}