{"id":"W4296356807","doi":"10.1016/j.crmeth.2022.100314","title":"iPSC-derived mesenchymal cells that support alveolar organoid development","year":2022,"lang":"en","type":"article","venue":"Cell Reports Methods","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Core Research for Evolutional Science and Technology; Japan Society for the Promotion of Science; Kitasato University; Fujiwara Memorial Foundation; Kyorin Pharmaceutical; Kyoto University; Canadian Internet Registration Authority; Japan Agency for Medical Research and Development","keywords":"Organoid; Mesenchyme; Induced pluripotent stem cell; Mesenchymal stem cell; Cell biology; Biology; Lung; Alveolar cells; Immunology; Pathology; Embryonic stem cell; Medicine; Internal medicine; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003745722,0.0003853047,0.000302769,0.0003830721,0.000231461,0.0003849244,0.000278842,0.0004005345,0.001649929],"category_scores_gemma":[0.0002891857,0.0001518582,0.0004150462,0.0002561927,0.0002252344,0.0002109241,0.0003699083,0.0008250787,0.001122399],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001256434,"about_ca_system_score_gemma":0.0002557337,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001964234,"about_ca_topic_score_gemma":0.0004201096,"domain_scores_codex":[0.9997321,0.00002930711,0.00004516169,0.00004686033,0.0001146995,0.00003192201],"domain_scores_gemma":[0.9997447,0.00005669956,0.00004540851,0.00006110546,0.00005405225,0.00003800643],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003859279,0.00002510316,0.0003057829,0.00007717311,0.000009118994,0.0001913081,0.00004428392,0.0002452442,0.9921793,0.0005236078,0.000294589,0.006066003],"study_design_scores_gemma":[0.00001409375,0.0001355328,0.002504204,0.00002836103,0.00004810908,0.0007508518,0.00004857781,0.001523752,0.9635394,0.0001989693,0.0311965,0.00001158635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6694041,0.00500012,0.2768685,0.0005147805,0.0006120129,0.00135538,0.01249851,0.001873396,0.03187316],"genre_scores_gemma":[0.8743825,0.004086964,0.09247004,0.0003771912,0.00009995802,0.0009146096,0.0134055,0.0003266747,0.01393662],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001649929,"threshold_uncertainty_score":0.005519509,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08472369062649138,"score_gpt":0.4162512216734936,"score_spread":0.3315275310470022,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}