{"id":"W4296356807","doi":"10.1016/j.crmeth.2022.100314","title":"iPSC-derived mesenchymal cells that support alveolar organoid development","year":2022,"lang":"en","type":"article","venue":"Cell Reports Methods","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Core Research for Evolutional Science and Technology; Japan Society for the Promotion of Science; Kitasato University; Fujiwara Memorial Foundation; Kyorin Pharmaceutical; Kyoto University; Canadian Internet Registration Authority; Japan Agency for Medical Research and Development","keywords":"Organoid; Mesenchyme; Induced pluripotent stem cell; Mesenchymal stem cell; Cell biology; Biology; Lung; Alveolar cells; Immunology; Pathology; Embryonic stem cell; Medicine; Internal medicine; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.008261253,0.0003370039,0.0006711256,0.0003698554,0.0006321672,0.00003281208,0.0002663684,0.000136225,0.01192554],"category_scores_gemma":[0.000546107,0.0003237684,0.0001879526,0.0006167096,0.0001206834,0.0001010287,0.0007897945,0.00114946,0.0001075771],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007452274,"about_ca_system_score_gemma":0.003975738,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003224401,"about_ca_topic_score_gemma":0.000001354063,"domain_scores_codex":[0.9942424,0.001000881,0.001020967,0.0009501592,0.001803659,0.0009819041],"domain_scores_gemma":[0.9969133,0.0003555221,0.0004423108,0.001180941,0.0002230999,0.0008848531],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002610336,0.0004509448,0.005316082,0.0007698757,0.00007587657,0.01587077,0.001178148,0.00002009602,0.8297706,0.000007144976,0.005448146,0.1408313],"study_design_scores_gemma":[0.0003492044,0.0002096972,0.002060407,0.000008284081,0.00002524783,0.00079381,0.000230354,0.00001625228,0.5060683,0.00002573656,0.490038,0.000174679],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.9305553,0.004197628,0.01059269,0.0008129369,0.003247042,0.003027107,0.00001093363,0.0004195076,0.04713687],"genre_scores_gemma":[0.3152689,0.0002104842,0.6048217,0.004393136,0.0002688626,0.0007516256,0.0001620566,0.0002919378,0.07383122],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.6152864,"threshold_uncertainty_score":0.9999214,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08472369062649138,"score_gpt":0.4162512216734936,"score_spread":0.3315275310470022,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}