{"id":"W4296382393","doi":"10.1097/01.tp.0000885364.42322.aa","title":"213.2: Preliminary Results of the First Clinical Trial to Prevent Graft Rejection in Heart Transplant Children Employing a Cellular Therapy With Autologous Treg Obtained From Thymic Tissue (thyTreg)","year":2022,"lang":"en","type":"article","venue":"Transplantation","topic":"Xenotransplantation and immune response","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; BC Children's Hospital","funders":"","keywords":"Medicine; Clinical trial; Tacrolimus; Transplantation; Cell therapy; Heart transplantation; Surgery; Immune system; Immunology; Internal medicine; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001621274,0.0008567085,0.001506272,0.0002615133,0.0003752486,0.0006872651,0.0004986851,0.001326169,0.004704285],"category_scores_gemma":[0.0007118698,0.0001878311,0.001063693,0.0001790456,0.0005125534,0.0003283795,0.0002567243,0.001696328,0.001096841],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003154267,"about_ca_system_score_gemma":0.0009921229,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004832985,"about_ca_topic_score_gemma":0.0006397055,"domain_scores_codex":[0.9995824,0.0001745828,0.00004494218,0.00005834338,0.00005755838,0.000082283],"domain_scores_gemma":[0.9993741,0.0001895878,0.00006496064,0.00007232088,0.00004812842,0.0002509289],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.3560351,0.1123922,0.01367913,0.002968892,0.00183146,0.00311288,0.0004927706,0.002418678,0.233138,0.0008410792,0.008482809,0.264607],"study_design_scores_gemma":[0.1426165,0.7812369,0.01819421,0.0001652614,0.0009085676,0.002272152,0.00005347745,0.0007671181,0.04239868,0.0002277001,0.01112806,0.00003144944],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9784591,0.005684031,0.0033556,0.001133862,0.0003273512,0.003693268,0.0022263,0.0001834434,0.004937034],"genre_scores_gemma":[0.9695049,0.004349284,0.006918741,0.00192965,0.0005324618,0.004139685,0.005144117,0.00006865356,0.007412603],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004704285,"threshold_uncertainty_score":0.01573741,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02471936623493528,"score_gpt":0.3037761515496915,"score_spread":0.2790567853147563,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}