{"id":"W4296468477","doi":"10.1016/s2152-2650(22)01464-1","title":"MPN-483 Thrombocytopenic Myelofibrosis (MF) Patients Previously Treated With a JAK Inhibitor in a Phase 3 Randomized Study of Momelotinib (MMB) versus Danazol (DAN) [MOMENTUM]","year":2022,"lang":"en","type":"article","venue":"Clinical Lymphoma Myeloma & Leukemia","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Gastroenterology; Internal medicine; Danazol; Placebo; Myelofibrosis; Ruxolitinib; Anemia; Hematocrit; Clinical endpoint; Randomized controlled trial; Surgery; Bone marrow; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001213014,0.001196743,0.002320797,0.0002980423,0.0004886527,0.001278309,0.0006980238,0.001159239,0.005566096],"category_scores_gemma":[0.001133107,0.0005634237,0.001713028,0.0003674643,0.000833712,0.0009520707,0.0003273037,0.003451594,0.0008103452],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007011493,"about_ca_system_score_gemma":0.001135745,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001142741,"about_ca_topic_score_gemma":0.004533563,"domain_scores_codex":[0.9996321,0.0001714799,0.00001731123,0.00006406338,0.00002325095,0.00009180708],"domain_scores_gemma":[0.99945,0.0001121417,0.00008668096,0.0000364056,0.00002604651,0.0002885835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9570853,0.006556415,0.002011572,0.0003299369,0.001387671,0.00008050814,0.0000528538,0.0004961915,0.004595786,0.0002122967,0.001815101,0.0253763],"study_design_scores_gemma":[0.9276076,0.06515495,0.004425505,0.00003176056,0.0007015711,0.00007141432,0.00002954461,0.0004237983,0.0003423438,0.0002030975,0.0009934549,0.00001497605],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890053,0.003467418,0.0004831059,0.001259456,0.0004242717,0.00141811,0.001169361,0.00009801768,0.002675053],"genre_scores_gemma":[0.9888805,0.002131117,0.001303509,0.001673038,0.0004123985,0.001291541,0.001638983,0.0000254958,0.002643408],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005566096,"threshold_uncertainty_score":0.01862043,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03399505292797916,"score_gpt":0.337825457765041,"score_spread":0.3038304048370619,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}