{"id":"W4296472985","doi":"10.1186/s12915-022-01402-3","title":"Combined nanometric and phylogenetic analysis of unique endocytic compartments in Giardia lamblia sheds light on the evolution of endocytosis in Metamonada","year":2022,"lang":"en","type":"article","venue":"BMC Biology","topic":"Parasitic Infections and Diagnostics","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Universität Zürich; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Biology; Endocytic cycle; Giardia lamblia; Endocytosis; Giardia; Phylogenetic tree; Protozoa; Cell biology; Evolutionary biology; Microbiology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002513379,0.0002145751,0.0002340492,0.001660975,0.0003691871,0.0004669122,0.0002637762,0.000548411,0.0006249913],"category_scores_gemma":[0.0004726726,0.0001377858,0.0002813393,0.0005965482,0.0003827992,0.0003419807,0.0006098028,0.0003230633,0.0003258326],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003324581,"about_ca_system_score_gemma":0.0001612682,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009913911,"about_ca_topic_score_gemma":0.001737198,"domain_scores_codex":[0.9998329,0.00001431836,0.00001475921,0.00007963003,0.00003290028,0.00002546469],"domain_scores_gemma":[0.9995851,0.00008131436,0.0001559387,0.00005823236,0.00007325034,0.00004612766],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00008704051,0.00001287187,0.04688323,0.0001001838,0.00002550362,0.00009116933,0.0002264832,0.0002135266,0.9445818,0.0001668479,0.00003842391,0.007572935],"study_design_scores_gemma":[0.000004724594,0.0001391047,0.9446713,0.00003303876,0.00006964512,0.001433894,0.000354462,0.003787177,0.04551652,0.0003198062,0.003649622,0.0000206101],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940209,0.0008035344,0.003961195,0.00003143054,0.000004435733,0.00001155185,0.0003807534,0.00005664116,0.0007295484],"genre_scores_gemma":[0.9915291,0.0002206139,0.007390237,0.00002613092,0.000004637473,0.00001919831,0.0005109455,0.00002154137,0.0002776407],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001660975,"threshold_uncertainty_score":0.0024122,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01655995846706372,"score_gpt":0.2524210928158423,"score_spread":0.2358611343487786,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}