{"id":"W4296531520","doi":"10.1016/s2152-2650(22)01225-3","title":"AML-131 ERG: From a Fortuitous Discovery to Potential Treatment for AML","year":2022,"lang":"en","type":"article","venue":"Clinical Lymphoma Myeloma & Leukemia","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Toronto","funders":"","keywords":"Erg; Biology; Myeloid; Cancer research; ETS transcription factor family; Haematopoiesis; Myeloid leukemia; Molecular biology; Transcription factor; Stem cell; Cell biology; Genetics; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002138288,0.0003767625,0.0005269751,0.0006355495,0.0004301157,0.002032867,0.0007037346,0.001603524,0.002957336],"category_scores_gemma":[0.002272429,0.0002371706,0.0003960466,0.0003674745,0.001722818,0.001764569,0.0010582,0.003804075,0.001109133],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001753507,"about_ca_system_score_gemma":0.00167877,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001117422,"about_ca_topic_score_gemma":0.002838919,"domain_scores_codex":[0.9995722,0.0001482494,0.0000324489,0.00004749862,0.0001124938,0.00008715969],"domain_scores_gemma":[0.9994461,0.000289119,0.0000437003,0.00005259241,0.00008327842,0.00008515589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0019442,0.0004959165,0.004087075,0.0007754259,0.0001887513,0.003084568,0.0003709994,0.001717966,0.03188217,0.1307095,0.07619231,0.7485512],"study_design_scores_gemma":[0.001027728,0.002189663,0.003724773,0.0006911071,0.0002447542,0.007191841,0.0002917109,0.001250886,0.03511164,0.05101221,0.8971599,0.0001038438],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"other","genre_scores_codex":[0.1204545,0.4365909,0.01533685,0.3200776,0.00607712,0.0002765591,0.001261281,0.0008408853,0.09908434],"genre_scores_gemma":[0.7170524,0.1802038,0.009832394,0.05128684,0.003101224,0.0001419508,0.0009952926,0.000267976,0.0371182],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.002957336,"threshold_uncertainty_score":0.01272267,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0463725433347081,"score_gpt":0.3594096536005253,"score_spread":0.3130371102658172,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}