{"id":"W4296533650","doi":"10.1016/s2152-2650(22)01554-3","title":"IBCL-249 Mosunetuzumab Monotherapy Is an Effective and Well-Tolerated Treatment Option for Patients With Relapsed/Refractory (R/R) Follicular Lymphoma (FL) Who Have Received ≥2 Prior Lines of Therapy: Pivotal Results From a Phase I/II Study","year":2022,"lang":"en","type":"article","venue":"Clinical Lymphoma Myeloma & Leukemia","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Roche (Canada); Princess Margaret Cancer Centre; Jewish General Hospital; Spinal Cord Injury BC; University of British Columbia","funders":"","keywords":"Medicine; Refractory (planetary science); Internal medicine; Dosing; Gastroenterology; Follicular lymphoma; Clinical endpoint; Surgery; Lymphoma; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004640071,0.0004051053,0.0009738568,0.0002470528,0.0002093056,0.0006702537,0.0003690202,0.0004755187,0.002881964],"category_scores_gemma":[0.0003014964,0.000198998,0.0005166508,0.0002072316,0.0002818817,0.0005249089,0.0001515065,0.001401764,0.0008196137],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004586717,"about_ca_system_score_gemma":0.0004012836,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000644523,"about_ca_topic_score_gemma":0.004225923,"domain_scores_codex":[0.9998785,0.00003777827,0.000006609696,0.00001686813,0.00001971207,0.00004060972],"domain_scores_gemma":[0.9998621,0.00002384789,0.00002889224,0.000008064603,0.000008795005,0.00006827738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1625437,0.01367478,0.01707767,0.00133544,0.001938808,0.0007188835,0.000217914,0.00252409,0.09030899,0.0006445893,0.01868897,0.6903261],"study_design_scores_gemma":[0.4150418,0.2864882,0.1962125,0.0007255185,0.002561421,0.003424949,0.0004307242,0.007371606,0.01984158,0.001293667,0.06643125,0.0001767134],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9749552,0.01514218,0.0004734103,0.001043121,0.0001788895,0.000414877,0.0007153237,0.0001645328,0.006912491],"genre_scores_gemma":[0.9910777,0.004123488,0.0007290588,0.0007401677,0.0001068594,0.0001382219,0.00107686,0.00001543418,0.00199231],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002881964,"threshold_uncertainty_score":0.009641171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02636925942745788,"score_gpt":0.3206130243264569,"score_spread":0.2942437648989991,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}