{"id":"W4296598430","doi":"10.21203/rs.3.rs-2010098/v1","title":"Adverse perinatal outcomes associated with prenatal exposure to protease- inhibitor-based versus non-nucleoside reverse transcriptase inhibitor-based antiretroviral combinations in pregnant women with HIV infection: a systematic review and meta-analysis","year":2022,"lang":"en","type":"review","venue":"Research Square","topic":"HIV/AIDS Research and Interventions","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Obstetrics; Low birth weight; Pregnancy; Meta-analysis; Gestation; Small for gestational age; Reverse-transcriptase inhibitor; Birth weight; Gestational age; Abortion; Adverse effect; Premature birth; Viral load; Human immunodeficiency virus (HIV); Antiretroviral therapy; Internal medicine; Immunology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01181685,0.002132144,0.01745979,0.005975887,0.0005670899,0.002444835,0.002167908,0.002075912,0.002634534],"category_scores_gemma":[0.03240328,0.001356087,0.02957214,0.007566459,0.0007001191,0.001257334,0.001269425,0.001427515,0.0002001669],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002266537,"about_ca_system_score_gemma":0.003388192,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006585846,"about_ca_topic_score_gemma":0.01208768,"domain_scores_codex":[0.9891413,0.005752917,0.002760355,0.001071341,0.00101506,0.0002589901],"domain_scores_gemma":[0.9715542,0.02142976,0.004626001,0.0005449079,0.001487704,0.000357464],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.002220843,0.00003536268,0.007960307,0.3499951,0.6296901,0.0002047915,0.00007700891,0.0005629964,0.0001816582,0.00007964674,0.0003660048,0.008626184],"study_design_scores_gemma":[0.0006419519,0.0003052182,0.004765932,0.01889429,0.9740813,0.000126041,0.0000427296,0.0002278776,0.0001202799,0.00009597954,0.0006773454,0.00002113974],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01283623,0.9849644,0.0006024334,0.0001535822,0.0001331805,0.0004199499,0.0006307334,0.00002228286,0.0002371009],"genre_scores_gemma":[0.3022781,0.6906729,0.002888195,0.0005957703,0.0002534006,0.00212079,0.0008518376,0.00002014576,0.0003188982],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01745979,"threshold_uncertainty_score":0.06249422,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08259625821103435,"score_gpt":0.3875236816215947,"score_spread":0.3049274234105604,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}