{"id":"W4296618007","doi":"10.1161/atvbaha.122.318177","title":"Regulated Necrosis in Atherosclerosis","year":2022,"lang":"en","type":"review","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":99,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity; University of Ottawa","funders":"","keywords":"Necroptosis; Pyroptosis; Necrosis; Programmed cell death; Medicine; Pathology; Macrophage; Tumor necrosis factor alpha; Vulnerable plaque; Apoptosis; Inflammation; Biology; Immunology; Inflammasome; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005550112,0.0007576708,0.001799124,0.00029287,0.0002720931,0.00006947001,0.0005557884,0.0008212579,0.0003400191],"category_scores_gemma":[0.00005605466,0.0007027746,0.0008934111,0.0004475732,0.0002734009,0.00001038894,0.0007240614,0.0004242081,0.00002628225],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006416005,"about_ca_system_score_gemma":0.0001224004,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001180769,"about_ca_topic_score_gemma":0.00009002716,"domain_scores_codex":[0.9963334,0.0006738814,0.0008994867,0.00123671,0.0001391242,0.0007174007],"domain_scores_gemma":[0.9984862,0.00004805192,0.0003382673,0.0009906136,0.00002795122,0.0001088764],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001955096,0.001337038,0.01492438,0.006441997,0.005009866,4.917891e-7,0.0008086116,0.000007954115,0.0446784,0.000497927,0.003009436,0.9232643],"study_design_scores_gemma":[0.0006726597,0.0004228555,0.01574308,0.0006784594,0.0003438698,0.000001245731,0.00006239586,0.000002566669,0.00001804492,0.00001733901,0.9812317,0.0008058224],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02762282,0.9705869,0.00001587487,0.00003632461,0.0003934224,0.0009233245,0.0001171825,0.00003864241,0.0002655392],"genre_scores_gemma":[0.002175599,0.9951835,0.00007723152,0.0001964662,0.0000927509,0.0005953276,0.00150975,0.0001380338,0.00003134698],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9782223,"threshold_uncertainty_score":0.9995424,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05473483393294706,"score_gpt":0.3128822998804078,"score_spread":0.2581474659474607,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}