{"id":"W4296642322","doi":"10.1007/s12325-022-02303-1","title":"Post-switch Effectiveness of Etanercept Biosimilar Versus Continued Etanercept in Rheumatoid Arthritis Patients with Stable Disease: A Prospective Multinational Observational Study","year":2022,"lang":"en","type":"article","venue":"Advances in Therapy","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Merck Canada Inc. (Canada); University of Saskatchewan; Université de Montréal; University of Toronto; St. Joseph's Hospital; Mount Sinai Hospital; Western University","funders":"","keywords":"Medicine; Etanercept; Rheumatoid arthritis; Internal medicine; Rheumatology; Erythrocyte sedimentation rate; Adverse effect; Observational study; Biosimilar; Methotrexate; Concomitant; Prospective cohort study; Physical therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007075952,0.0002028628,0.0004305127,0.0001557505,0.0001347894,0.000007271633,0.0001913598,0.00006253809,0.0005781001],"category_scores_gemma":[0.0001472639,0.0001674631,0.00005942613,0.0005018691,0.0002058082,0.0002132612,0.00007838281,0.0003368069,0.000001360309],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001438318,"about_ca_system_score_gemma":0.00009963881,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005987763,"about_ca_topic_score_gemma":0.0001526465,"domain_scores_codex":[0.9976994,0.001043713,0.0003755562,0.0004304403,0.000174015,0.0002769078],"domain_scores_gemma":[0.9985875,0.0008202146,0.0001658332,0.0001964509,0.0002072869,0.00002271121],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0195183,0.003259122,0.960575,0.00001688754,0.000140004,0.00001082442,0.0005118919,0.0002947376,0.003382596,0.0006824629,0.000006310001,0.0116018],"study_design_scores_gemma":[0.01915675,0.002155905,0.9739935,0.00006032978,0.000007602592,0.000001317708,0.0006826776,0.00001870583,0.001340613,0.0004355252,0.001922774,0.0002242284],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906528,0.00704791,0.0000432536,0.00008305596,0.0003252761,0.001371876,0.000363403,0.00001908769,0.00009333884],"genre_scores_gemma":[0.9982787,0.0006089605,0.0003867158,0.00008642361,0.00000481113,0.0004014235,0.0001642227,0.00001747081,0.00005127947],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01341851,"threshold_uncertainty_score":0.6828949,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01895463268009967,"score_gpt":0.3013498490173185,"score_spread":0.2823952163372188,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}