{"id":"W4296702970","doi":"10.1101/2022.09.20.508718","title":"Peroxisome biogenesis initiated by protein phase separation","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Université du Québec à Montréal","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Peroxisome; Biogenesis; Organelle; Transmembrane protein; Protein targeting; Transport protein; Cell biology; Saccharomyces cerevisiae; Biophysics; Organelle biogenesis; Biology; Biochemistry; Membrane protein; Chemistry; Yeast; Membrane; Receptor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001121466,0.0002972449,0.0002064971,0.0002269927,0.0001890048,0.0002943669,0.0001435306,0.0002332731,0.001501721],"category_scores_gemma":[0.0001381529,0.0001196368,0.0003076269,0.0001316389,0.000218862,0.0002940003,0.0004015568,0.0005587198,0.0008729816],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004039846,"about_ca_system_score_gemma":0.0001924052,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002582833,"about_ca_topic_score_gemma":0.0001731968,"domain_scores_codex":[0.9999026,0.00001521069,0.000005249872,0.00002675269,0.00002858148,0.00002152211],"domain_scores_gemma":[0.9998341,0.00003310629,0.00005250105,0.00001961477,0.00002745673,0.00003329744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001508239,0.00001552685,0.0004216668,0.0001015335,0.000007471507,0.0002773455,0.00001791221,0.0001564549,0.9954803,0.001235331,0.0002472051,0.001888462],"study_design_scores_gemma":[0.00002798399,0.0001213313,0.004749507,0.00001894547,0.00001229067,0.0007620525,0.00002603544,0.003817886,0.9813892,0.001483334,0.007582094,0.000009328901],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9424251,0.004592036,0.04208,0.0004447389,0.0002155538,0.0001187335,0.0009735507,0.001258272,0.007891975],"genre_scores_gemma":[0.989229,0.0008122966,0.004641084,0.0001428072,0.00004139259,0.00005374232,0.0009528288,0.00005595708,0.004071026],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001501721,"threshold_uncertainty_score":0.005023718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02043496256143513,"score_gpt":0.2875843687573595,"score_spread":0.2671494061959244,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}