{"id":"W4296703857","doi":"10.1091/mbc.e22-06-0218","title":"Inositol 1, 4, 5-trisphosphate receptor is required for spindle assembly in <i>Xenopus</i> oocytes","year":2022,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Ottawa Hospital","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research","keywords":"Inositol trisphosphate receptor; Cell biology; Biology; Calcium; Inositol; Germinal vesicle; Cytoplasm; Xenopus; BAPTA; Calcium signaling; Calcium in biology; Spindle apparatus; Endoplasmic reticulum; Microtubule; Mitosis; Oocyte; Intracellular; Receptor; Biochemistry; Cell; Chemistry; Cell division","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001696597,0.0002273388,0.0002823954,0.0001977493,0.0002146514,0.0005985068,0.0003108846,0.000250623,0.001910674],"category_scores_gemma":[0.0002377731,0.0002784804,0.0002605176,0.0001073417,0.0001899589,0.0003343752,0.0001723902,0.0005393202,0.001104359],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004974796,"about_ca_system_score_gemma":0.0002582245,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002337101,"about_ca_topic_score_gemma":0.003857238,"domain_scores_codex":[0.9998559,0.00001503938,0.00002256998,0.0000341314,0.00003844067,0.0000339599],"domain_scores_gemma":[0.9997833,0.00004197641,0.00007074563,0.00001994217,0.00003552856,0.00004848506],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002331133,0.000004641132,0.00008244935,0.00001223362,0.000001484813,0.0000330053,0.000008427825,0.00001068297,0.9995364,0.00005850584,0.00002228985,0.0002065436],"study_design_scores_gemma":[0.00003007555,0.00006329258,0.006541599,0.000007834175,0.000009041165,0.0002282342,0.00003039564,0.0006496503,0.990491,0.00003916188,0.001905672,0.000003944944],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894052,0.001078092,0.004607578,0.0002165937,0.00003228903,0.00004169952,0.000680752,0.0002173081,0.00372033],"genre_scores_gemma":[0.989926,0.0006014011,0.003097798,0.0001047848,0.00001441607,0.00004344516,0.001123281,0.0001620184,0.004926976],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002337101,"threshold_uncertainty_score":0.006391883,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00626648341437664,"score_gpt":0.2383485299248997,"score_spread":0.232082046510523,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}