{"id":"W4296741057","doi":"10.1016/j.msard.2022.104190","title":"Linking X to MS: Immunity and demyelination on the X-chromosome in MS","year":2022,"lang":"en","type":"letter","venue":"Multiple Sclerosis and Related Disorders","topic":"Reproductive System and Pregnancy","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation","funders":"","keywords":"Multiple sclerosis; Medicine; Immunity; X chromosome; Chromosome; Immunology; Neuroscience; Genetics; Immune system; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001382069,0.0008393172,0.001223798,0.0007367251,0.001784031,0.001819661,0.0009939815,0.02558622,0.003462466],"category_scores_gemma":[0.007150016,0.0004985841,0.0005704734,0.000518448,0.001907973,0.002538534,0.0007769364,0.01190935,0.001488842],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001558998,"about_ca_system_score_gemma":0.0009911121,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001438814,"about_ca_topic_score_gemma":0.002007479,"domain_scores_codex":[0.9989647,0.0004928056,0.0001198641,0.0001109562,0.0001818196,0.0001298273],"domain_scores_gemma":[0.9971229,0.002094353,0.0001709362,0.00009464981,0.0002167488,0.0003003914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00099317,0.0003403262,0.01180462,0.0005537014,0.0001048616,0.1473255,0.0007731527,0.0006645,0.002650839,0.01649718,0.7696161,0.048676],"study_design_scores_gemma":[0.001457295,0.0008717836,0.01741684,0.001568928,0.0002818738,0.2393757,0.002315123,0.006446901,0.001961472,0.07940226,0.6486568,0.0002449483],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.01032991,0.01711462,0.0003999779,0.9288956,0.03391164,0.00002710406,0.00003530723,0.00003721548,0.009248682],"genre_scores_gemma":[0.0892634,0.01702415,0.0004818683,0.432852,0.4477922,0.00005744053,0.00003472597,0.00003834116,0.01245581],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02558622,"threshold_uncertainty_score":0.01158309,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0246551719435279,"score_gpt":0.2157133270172138,"score_spread":0.1910581550736859,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}