{"id":"W4296758434","doi":"10.3390/pharmaceutics14102014","title":"Recent Advances in Multifunctional Antimicrobial Peptides as Immunomodulatory and Anticancer Therapy: Chromogranin A-Derived Peptides and Dermaseptins as Endogenous versus Exogenous Actors","year":2022,"lang":"en","type":"review","venue":"Pharmaceutics","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Antimicrobial peptides; Chromogranin A; Endogeny; Antimicrobial; Context (archaeology); Biology; Computational biology; Immunology; Microbiology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004465799,0.0006517718,0.00086187,0.001754705,0.0001787319,0.0007821408,0.0005241742,0.0008155524,0.00265119],"category_scores_gemma":[0.0005183798,0.0002127423,0.0003927394,0.001760084,0.000316214,0.00122739,0.0005274249,0.001633461,0.001160741],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003955701,"about_ca_system_score_gemma":0.0005809363,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003958541,"about_ca_topic_score_gemma":0.0007287209,"domain_scores_codex":[0.9998691,0.00002510394,0.00001905425,0.00002705263,0.00004400642,0.00001571745],"domain_scores_gemma":[0.9997608,0.0001205797,0.00002987278,0.00000672853,0.00005326811,0.00002871846],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001182969,0.0001187554,0.0001917188,0.01712296,0.00009373518,0.0002781457,0.00009018002,0.0004796725,0.004782343,0.00401634,0.02652526,0.9461825],"study_design_scores_gemma":[0.00002089575,0.0001644991,0.0006395975,0.001655308,0.0001044656,0.001157824,0.0000491428,0.0001287672,0.0008334067,0.001287793,0.9939417,0.00001659342],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001975736,0.9984357,0.0001408932,0.0002082661,0.0002284128,0.00000332286,0.00001060952,0.000006356493,0.0007688696],"genre_scores_gemma":[0.0009285453,0.9978451,0.0001985121,0.0002323675,0.0002659641,0.000006299913,0.0000279945,0.000001679401,0.0004935189],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00265119,"threshold_uncertainty_score":0.008869112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.108548398900556,"score_gpt":0.3479833577370178,"score_spread":0.2394349588364618,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}