{"id":"W4296758434","doi":"10.3390/pharmaceutics14102014","title":"Recent Advances in Multifunctional Antimicrobial Peptides as Immunomodulatory and Anticancer Therapy: Chromogranin A-Derived Peptides and Dermaseptins as Endogenous versus Exogenous Actors","year":2022,"lang":"en","type":"review","venue":"Pharmaceutics","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Antimicrobial peptides; Chromogranin A; Endogeny; Antimicrobial; Context (archaeology); Biology; Computational biology; Immunology; Microbiology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003342517,0.0009526454,0.001723052,0.00039495,0.0007437483,0.00009295692,0.0003789039,0.0004522648,0.001417231],"category_scores_gemma":[0.0000863435,0.0008944131,0.0003476999,0.0003134349,0.0009264719,0.0003378,0.0004256281,0.001422567,0.00009449056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003042927,"about_ca_system_score_gemma":0.0005341982,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001664313,"about_ca_topic_score_gemma":0.00005731513,"domain_scores_codex":[0.9965947,0.0005884719,0.0008272565,0.0009706744,0.0001243485,0.0008945951],"domain_scores_gemma":[0.9981591,0.0008053664,0.0005395317,0.0003443617,0.00005988637,0.00009176657],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007739445,0.0003835823,0.00006523982,0.001251384,0.0009400977,0.0001242758,0.0008560712,0.000008200735,0.02920066,0.00003009322,0.000176543,0.9661899],"study_design_scores_gemma":[0.002796884,0.0003518994,0.00001969546,0.0007954184,0.0005428146,0.001447358,0.0004530803,0.000001567598,0.006101659,0.00001164793,0.986553,0.000925008],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0662748,0.9294624,0.000001004207,0.00003658866,0.002040559,0.001130409,0.0003958491,0.0001013308,0.0005570489],"genre_scores_gemma":[0.02338217,0.9750457,0.00005135101,0.000298632,0.0001288545,0.000123248,0.0005990981,0.0001434297,0.0002274859],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9863764,"threshold_uncertainty_score":0.9994956,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.108548398900556,"score_gpt":0.3479833577370178,"score_spread":0.2394349588364618,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}