{"id":"W4296794856","doi":"10.3390/toxins14090640","title":"Ochratoxin A and Citrinin Differentially Modulate Bovine Mammary Epithelial Cell Permeability and Innate Immune Function","year":2022,"lang":"en","type":"article","venue":"Toxins","topic":"Milk Quality and Mastitis in Dairy Cows","field":"Agricultural and Biological Sciences","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Alltech","keywords":"Citrinin; Innate immune system; TLR4; Biology; Occludin; Paracellular transport; Immune system; Epithelium; Ochratoxin A; Andrology; Tight junction; Cell biology; Immunology; Mycotoxin; Biochemistry; Food science; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003750856,0.0001293078,0.0001727327,0.00001363956,0.0004424695,0.00005614101,0.0001537349,0.00005226051,0.001027361],"category_scores_gemma":[0.0000239272,0.00006313549,0.00005022577,0.0001482361,0.00007162278,0.0001120172,0.00047799,0.0001959267,0.000005001999],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002055111,"about_ca_system_score_gemma":0.000008691607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002368365,"about_ca_topic_score_gemma":0.0002368397,"domain_scores_codex":[0.9988526,0.0002128228,0.000212807,0.0003370136,0.000179546,0.0002052229],"domain_scores_gemma":[0.9996672,0.00007704118,0.00006821755,0.00008314462,0.00002052673,0.00008391776],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003107164,0.0002465102,0.003082103,0.00003447553,0.00001566301,0.00001098245,0.0003179522,0.000008291756,0.9152408,0.002180371,0.0002042128,0.07834795],"study_design_scores_gemma":[0.0009926343,0.001860937,0.9404616,0.000011171,0.00003682774,0.00003895986,0.0004630932,0.001009342,0.0076537,0.008565309,0.03839989,0.0005065576],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971445,0.0004756393,0.00004585804,0.0009811451,0.0002047587,0.0001802854,0.0001666719,0.00006855352,0.0007326473],"genre_scores_gemma":[0.9981001,0.0001482465,0.00004563414,0.0002565447,0.00009681937,0.00002605428,0.00006992387,0.000001122736,0.00125554],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9373795,"threshold_uncertainty_score":0.9998859,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01428477894281871,"score_gpt":0.2022794391561119,"score_spread":0.1879946602132932,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}