{"id":"W4296799598","doi":"10.1097/adm.0000000000001072","title":"48-hour Induction of Transdermal Buprenorphine to Sublingual Buprenorphine/Naloxone: The IPPAS Method","year":2022,"lang":"en","type":"article","venue":"Journal of Addiction Medicine","topic":"Opioid Use Disorder Treatment","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Mental Health & Substance Use Services; Provincial Health Services Authority","funders":"","keywords":"Buprenorphine; Medicine; (+)-Naloxone; Transdermal; Opioid use disorder; Fentanyl; Anesthesia; Opioid; Pharmacology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002248328,0.000258642,0.0007717021,0.0007913703,0.0002956625,0.000008258343,0.0002690974,0.00007490155,0.002869358],"category_scores_gemma":[0.0004433076,0.000164127,0.0002697461,0.001153103,0.0001043731,0.0001415652,0.00006296868,0.001099593,0.000007854139],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002909975,"about_ca_system_score_gemma":0.0003410288,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002471646,"about_ca_topic_score_gemma":0.00001123177,"domain_scores_codex":[0.9962598,0.0003892994,0.001256154,0.0002405516,0.001574826,0.0002793809],"domain_scores_gemma":[0.9976995,0.0002281544,0.0008044629,0.00037791,0.0005907721,0.0002992061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01850634,0.006338765,0.01934299,0.0005090317,0.005854572,0.0009676763,0.07965596,0.01569321,0.3083411,0.0007343519,0.3161203,0.2279356],"study_design_scores_gemma":[0.05085597,0.04466872,0.2677551,0.001613511,0.01041123,0.02208017,0.05428024,0.002193396,0.03743696,0.001019852,0.5066705,0.001014414],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8907961,0.004180922,0.01251096,0.08684444,0.003742501,0.0009446132,0.00005853451,0.00005987273,0.0008620982],"genre_scores_gemma":[0.9905341,0.000313925,0.004288119,0.001618242,0.002385106,0.00003574585,0.00005195623,0.00005333272,0.0007194542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2709042,"threshold_uncertainty_score":0.9980422,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02070232259174483,"score_gpt":0.3137447724160272,"score_spread":0.2930424498242824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}