{"id":"W4296805220","doi":"10.3390/cells11182858","title":"The Role of Neutrophils in Oncolytic Orf Virus-Mediated Cancer Immunotherapy","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research","keywords":"Oncolytic virus; Virotherapy; Immunotherapy; Effector; Cancer; Tumor microenvironment; Immunology; Cancer research; Innate immune system; Virus; Cancer immunotherapy; Tumor necrosis factor alpha; Biology; Medicine; Virology; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003852965,0.0003037983,0.0002089199,0.0001563625,0.0001321325,0.0003205509,0.0001263607,0.0002889164,0.0005086409],"category_scores_gemma":[0.0001295681,0.000078006,0.0001062945,0.00006358419,0.0002324046,0.000350198,0.0002212126,0.000366804,0.0001108591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002288534,"about_ca_system_score_gemma":0.0002482303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002470375,"about_ca_topic_score_gemma":0.0002982535,"domain_scores_codex":[0.9998277,0.00008909305,0.000009762889,0.00001908697,0.00002398451,0.00003036035],"domain_scores_gemma":[0.9999552,0.00001205076,0.00001186693,0.000003923503,0.000006730897,0.00001027429],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001005395,0.0001223471,0.002682882,0.0003004582,0.00001270292,0.0004765212,0.0001179754,0.0004595305,0.960816,0.003189565,0.0002151059,0.03060135],"study_design_scores_gemma":[0.0001458403,0.004431738,0.03140446,0.0001794553,0.0001129609,0.003401767,0.0004315979,0.006756734,0.9179747,0.003135333,0.03199958,0.00002577231],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9308648,0.05178283,0.01164281,0.0008388486,0.0001240657,0.0001800119,0.0001248798,0.00005921338,0.004382589],"genre_scores_gemma":[0.9869287,0.008335764,0.00265526,0.00009636324,0.00003263826,0.0000659348,0.00005220964,0.000003231237,0.001829772],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005086409,"threshold_uncertainty_score":0.002037704,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008124616556548671,"score_gpt":0.2728716777258917,"score_spread":0.264747061169343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}