{"id":"W4296805220","doi":"10.3390/cells11182858","title":"The Role of Neutrophils in Oncolytic Orf Virus-Mediated Cancer Immunotherapy","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research","keywords":"Oncolytic virus; Virotherapy; Immunotherapy; Effector; Cancer; Tumor microenvironment; Immunology; Cancer research; Innate immune system; Virus; Cancer immunotherapy; Tumor necrosis factor alpha; Biology; Medicine; Virology; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003774055,0.00009599053,0.0001124136,0.00004510894,0.0001029573,0.00001110027,0.0004243022,0.00004723376,0.0001901731],"category_scores_gemma":[0.000009674824,0.0000798523,0.00006759374,0.0002000238,0.00009125814,0.000001378854,0.0001323054,0.0001665705,0.00000732019],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006040579,"about_ca_system_score_gemma":0.000229589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000222417,"about_ca_topic_score_gemma":0.0004464849,"domain_scores_codex":[0.9989322,0.0001941907,0.0001967449,0.0002023184,0.0002058845,0.0002686011],"domain_scores_gemma":[0.9994201,0.00003844397,0.0000714564,0.0003950218,0.00003857478,0.00003640822],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001458237,0.00007896835,0.000759062,0.000002716435,0.00003615437,0.000001935644,0.00007328547,0.0009482831,0.9886643,0.000007006694,0.0003762202,0.007593806],"study_design_scores_gemma":[0.0006099362,0.0009188947,0.0005170535,0.000001891396,0.00000184631,7.368473e-7,0.0001079055,0.0001241678,0.8726403,0.00007449782,0.1249165,0.0000862813],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869352,0.01211474,0.000001458681,0.0001324925,0.0001158888,0.0002605814,0.00005051411,0.000007144329,0.0003819795],"genre_scores_gemma":[0.9950193,0.003905766,0.00000665324,0.0002365441,0.00006813629,0.0001681295,0.00002270937,0.00003703649,0.0005357689],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1245403,"threshold_uncertainty_score":0.3256282,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008124616556548671,"score_gpt":0.2728716777258917,"score_spread":0.264747061169343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}