{"id":"W4296809690","doi":"10.1111/jth.15892","title":"Long‐term follow‐up of patients treated with caplacizumab and safety and efficacy of repeat caplacizumab use: Post‐HERCULES study","year":2022,"lang":"en","type":"article","venue":"Journal of Thrombosis and Haemostasis","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":38,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Sanofi","keywords":"Medicine; Placebo; Internal medicine; Population; Adverse effect; Surgery; Gastroenterology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003182685,0.0002207732,0.000834614,0.0002190483,0.0002921985,0.00002372577,0.0001540513,0.00005563119,0.000328612],"category_scores_gemma":[0.00007660654,0.0001658884,0.0001068667,0.0001420568,0.0002097021,0.0001737543,0.0002348926,0.0001833728,3.959885e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006421765,"about_ca_system_score_gemma":0.00005786804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002987517,"about_ca_topic_score_gemma":0.0001072695,"domain_scores_codex":[0.9981425,0.0004321682,0.0008162124,0.0002454754,0.0001661223,0.0001974942],"domain_scores_gemma":[0.9982631,0.0002876636,0.0008714644,0.0002424909,0.0002850723,0.00005016337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.007297182,0.001576103,0.9768976,0.0001078722,0.002065993,0.00001402989,0.002769579,0.000004659998,0.002245802,0.000008107259,0.0006147517,0.006398336],"study_design_scores_gemma":[0.01737889,0.004590223,0.9722334,0.0001505844,0.0009746616,0.0001201276,0.002821634,6.176024e-7,0.001348566,0.000002194799,0.0002152524,0.0001639073],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996094,0.002569882,0.000002995951,0.000072824,0.0001292735,0.0005282467,0.0005821711,0.000006413261,0.00001420155],"genre_scores_gemma":[0.9993719,0.0004356988,0.00002962388,0.00002056546,0.00000653155,0.000005766984,0.00005966603,0.00001803646,0.00005221263],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01008171,"threshold_uncertainty_score":0.6764734,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03461727290857151,"score_gpt":0.2823399840418522,"score_spread":0.2477227111332806,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}