{"id":"W4296912099","doi":"10.1101/2022.09.21.508851","title":"Mortality without springing a leak: Locust gut epithelia do not become more permeable to fluorescent dextran and bacteria in the cold","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Insect Utilization and Effects","field":"Agricultural and Biological Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Locust; Bacteria; Paracellular transport; Hemolymph; Gut flora; Dextran; Insect; Microbiome; Microbiology; Cell biology; Immune system; Biochemistry; Botany; Permeability (electromagnetism); Immunology; Bioinformatics; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001426642,0.0004991368,0.0005164968,0.0000715268,0.0004664221,0.0005151794,0.0008081896,0.0002710339,0.0004571309],"category_scores_gemma":[0.0001491824,0.0002487562,0.0001287169,0.0007599805,0.00009995599,0.0001271263,0.0006959398,0.0007387096,0.0000191978],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002048431,"about_ca_system_score_gemma":0.0000823504,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008800762,"about_ca_topic_score_gemma":0.0003189941,"domain_scores_codex":[0.9969212,0.0003935602,0.000477547,0.001004196,0.0005409036,0.0006625357],"domain_scores_gemma":[0.9988394,0.0001197077,0.0002143949,0.0004413805,0.0001354434,0.0002496663],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00004849627,0.0001461699,0.1385361,0.000162218,0.00003432897,0.00004647339,0.0001097934,0.0001724692,0.8603274,0.0003205302,0.00008367155,0.00001241648],"study_design_scores_gemma":[0.0002341583,0.00007438453,0.9701205,0.0001974233,0.00004361164,6.96018e-8,0.00006010609,0.0005664161,0.01825964,0.000001179859,0.009844224,0.0005982862],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964954,0.0001858704,0.00001467687,0.001020913,0.0004594834,0.001340579,0.0003092073,0.0001601158,0.00001369914],"genre_scores_gemma":[0.9979222,0.0001053715,0.0002090661,0.001127194,0.0002795383,0.0003325945,0.000002008437,0.00001311553,0.000008852022],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8420677,"threshold_uncertainty_score":0.9999965,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02306832346710919,"score_gpt":0.2377050367002112,"score_spread":0.214636713233102,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}