{"id":"W4296965222","doi":"10.1016/s2152-2650(22)00742-x","title":"Poster: AML-432 Overall Survival (OS) by IDH2 Mutant Allele (R140 or R172) in Patients With Late-Stage, Mutant-IDH2 Relapsed/Refractory Acute Myeloid Leukemia (AML) Treated With Enasidenib or Conventional Care Regimens (CCR) in the Randomized, Open-Label, Phase 3 IDHENTIFY Trial","year":2022,"lang":"en","type":"article","venue":"Clinical Lymphoma Myeloma & Leukemia","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"IDH2; Myeloid leukemia; Refractory (planetary science); Mutant; Medicine; Internal medicine; Stage (stratigraphy); Oncology; IDH1; Cancer research; Biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001152214,0.000901863,0.001423964,0.0001853381,0.0002984162,0.0009489132,0.0004621472,0.0008973193,0.01041024],"category_scores_gemma":[0.0006956685,0.0002500146,0.001908467,0.0002094481,0.0004638371,0.0005371015,0.0003931663,0.002805189,0.001004855],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005948631,"about_ca_system_score_gemma":0.0009520199,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005839763,"about_ca_topic_score_gemma":0.002244414,"domain_scores_codex":[0.9996793,0.0001560694,0.00001435119,0.00005858573,0.0000241771,0.00006753171],"domain_scores_gemma":[0.9995765,0.00008878807,0.00007363928,0.00002856453,0.00002418599,0.0002083572],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9311904,0.00389176,0.003120626,0.0006431158,0.001750109,0.00005221695,0.00006169082,0.0011148,0.005429599,0.0002764477,0.01004838,0.04242093],"study_design_scores_gemma":[0.8188954,0.1385439,0.02504775,0.0001587859,0.003374836,0.0001433161,0.00008058843,0.00131546,0.002899484,0.0008082641,0.008682655,0.00004967874],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9778998,0.006577905,0.0004907561,0.002673355,0.001101736,0.0009415807,0.004688474,0.0001436033,0.005482725],"genre_scores_gemma":[0.9784476,0.003612448,0.0007334165,0.002483377,0.0009325914,0.0009359433,0.004793469,0.00004712374,0.008014061],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01041024,"threshold_uncertainty_score":0.03482574,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04324224856268057,"score_gpt":0.3537400234238035,"score_spread":0.3104977748611229,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}