{"id":"W4296992822","doi":"10.3390/cells11192957","title":"Bioinformatics and Functional Analysis of a New Nuclear Localization Sequence of the Influenza A Virus Nucleoprotein","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Nucleoprotein; Biology; Nuclear localization sequence; Nuclear transport; Nuclear export signal; Mutagenesis; NLS; Genome; Influenza A virus; Virus; Green fluorescent protein; Nuclear protein; Genetics; Viral replication; Virology; N-terminus; Gene; Cell nucleus; Computational biology; Peptide sequence; Mutation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001225721,0.00005320052,0.00009679794,0.00004530148,0.00007347248,0.000005104182,0.0001031486,0.00003615026,0.0001887786],"category_scores_gemma":[0.00001955197,0.00004361381,0.00007439794,0.0002537772,0.00004508785,0.000002628205,0.0001367043,0.00003093197,8.90971e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006171771,"about_ca_system_score_gemma":0.00004389193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006143301,"about_ca_topic_score_gemma":0.000006261821,"domain_scores_codex":[0.9995097,0.00004190767,0.0001683404,0.00008731479,0.0001330982,0.0000596728],"domain_scores_gemma":[0.9995956,0.000005734893,0.0001463751,0.0001998594,0.00002864633,0.00002377534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003720957,0.00001464404,0.0001932505,0.00001382881,0.0001074314,7.8389e-8,0.0001893767,0.005127679,0.9924721,0.0001812874,0.0002372057,0.001425868],"study_design_scores_gemma":[0.0001536784,0.0001047764,0.0004581548,0.000004758182,0.0001372317,0.000001455497,0.0001917045,0.004037859,0.9762294,0.0001485433,0.01846331,0.00006910673],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927685,0.0001814964,0.006533261,0.00002769868,0.00005357345,0.0001548383,0.00007069882,0.000003165378,0.0002067716],"genre_scores_gemma":[0.9984834,0.00002160413,0.0009642176,0.0003227658,0.00001271628,0.000005207151,0.00001590272,0.000006842319,0.0001673554],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0182261,"threshold_uncertainty_score":0.2066993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01883661225516907,"score_gpt":0.2257670778427117,"score_spread":0.2069304655875427,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}