{"id":"W4296992822","doi":"10.3390/cells11192957","title":"Bioinformatics and Functional Analysis of a New Nuclear Localization Sequence of the Influenza A Virus Nucleoprotein","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Nucleoprotein; Biology; Nuclear localization sequence; Nuclear transport; Nuclear export signal; Mutagenesis; NLS; Genome; Influenza A virus; Virus; Green fluorescent protein; Nuclear protein; Genetics; Viral replication; Virology; N-terminus; Gene; Cell nucleus; Computational biology; Peptide sequence; Mutation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004918327,0.0005983296,0.0006480903,0.001396424,0.0005145111,0.0005953126,0.0003638862,0.0004457133,0.002172788],"category_scores_gemma":[0.0009761191,0.0001586374,0.0009860242,0.001187866,0.0002010107,0.0002957932,0.0002604093,0.0004088403,0.001807692],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005310602,"about_ca_system_score_gemma":0.0006876444,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001491424,"about_ca_topic_score_gemma":0.0021196,"domain_scores_codex":[0.9996133,0.00006375463,0.00004077041,0.0001226773,0.0001223378,0.00003713823],"domain_scores_gemma":[0.9995059,0.0001643209,0.00009358743,0.00004097541,0.0001182857,0.00007691313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002372389,0.0004670606,0.0343531,0.001431307,0.0002907686,0.002946337,0.0003069518,0.00849889,0.9013213,0.001483598,0.004733079,0.04179523],"study_design_scores_gemma":[0.0003150145,0.002459682,0.2458694,0.0002111636,0.0008455307,0.008568265,0.0006573041,0.3163675,0.3563574,0.002630982,0.06554449,0.0001732553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9403468,0.001883831,0.03062908,0.0003067566,0.0001011839,0.0001715484,0.02089289,0.002254471,0.003413397],"genre_scores_gemma":[0.8677647,0.0007382272,0.05584841,0.0001470769,0.00004127374,0.0001719146,0.0731978,0.0003154583,0.001775087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002172788,"threshold_uncertainty_score":0.007268727,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01883661225516907,"score_gpt":0.2257670778427117,"score_spread":0.2069304655875427,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}