{"id":"W4297037772","doi":"10.1111/jon.13055","title":"Related amyloid burden and cortical atrophy in individuals with subtle cognitive decline","year":2022,"lang":"en","type":"article","venue":"Journal of Neuroimaging","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; National Institute of General Medical Sciences; National Institute on Aging; Genentech; Lundbeckfonden; GE Healthcare; BioClinica; Fujirebio US; Pfizer; Novartis Pharmaceuticals Corporation; Alzheimer's Drug Discovery Foundation; Merck; Takeda Pharmaceutical Company; Eli Lilly and Company; Foundation for the National Institutes of Health; U.S. Department of Defense; Canadian Institutes of Health Research; National Science Foundation","keywords":"Atrophy; Entorhinal cortex; Pittsburgh compound B; Medicine; Cognitive decline; Cognition; Neuroimaging; Hippocampus; Dementia; Neuroscience; Temporal lobe; Amyloid (mycology); Pathological; Alzheimer's disease; Hippocampal formation; Disease; Pathology; Internal medicine; Psychology; Psychiatry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003991144,0.0004470019,0.0003406789,0.0009685858,0.0006401184,0.0004734568,0.0002820704,0.0004384809,0.001201594],"category_scores_gemma":[0.001983447,0.0002233791,0.0002650781,0.0006070926,0.0003337331,0.0003651087,0.000493725,0.000468615,0.0001489904],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000332668,"about_ca_system_score_gemma":0.0002458001,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007997625,"about_ca_topic_score_gemma":0.01403325,"domain_scores_codex":[0.9998146,0.00003683433,0.00002066453,0.00006608263,0.00003452595,0.00002738379],"domain_scores_gemma":[0.9994518,0.00009820872,0.000255478,0.00004566115,0.00005880855,0.0000900554],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002947076,0.00006287001,0.9964797,0.00001240868,0.00008283921,0.0001711997,0.0002535656,0.0001361914,0.0005146886,0.00003075302,0.000103823,0.001857286],"study_design_scores_gemma":[0.000007083845,0.00005180915,0.9990593,0.000002239679,0.00001977712,0.00036287,0.0001092544,0.0001859282,0.00007070802,0.00009589997,0.00003291422,0.00000238171],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997954,0.00003557136,0.00002362197,0.00001244949,8.423737e-7,0.000002440608,0.00004290697,0.000001228347,0.00008558041],"genre_scores_gemma":[0.999765,0.00001846179,0.00006056396,0.000006872924,0.000002754322,0.000002967017,0.00007978775,7.265554e-7,0.0000627695],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007997625,"threshold_uncertainty_score":0.01590216,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01585760554495875,"score_gpt":0.3050963753570647,"score_spread":0.289238769812106,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}