{"id":"W4297037772","doi":"10.1111/jon.13055","title":"Related amyloid burden and cortical atrophy in individuals with subtle cognitive decline","year":2022,"lang":"en","type":"article","venue":"Journal of Neuroimaging","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; National Institute of General Medical Sciences; National Institute on Aging; Genentech; Lundbeckfonden; GE Healthcare; BioClinica; Fujirebio US; Pfizer; Novartis Pharmaceuticals Corporation; Alzheimer's Drug Discovery Foundation; Merck; Takeda Pharmaceutical Company; Eli Lilly and Company; Foundation for the National Institutes of Health; U.S. Department of Defense; Canadian Institutes of Health Research; National Science Foundation","keywords":"Atrophy; Entorhinal cortex; Pittsburgh compound B; Medicine; Cognitive decline; Cognition; Neuroimaging; Hippocampus; Dementia; Neuroscience; Temporal lobe; Amyloid (mycology); Pathological; Alzheimer's disease; Hippocampal formation; Disease; Pathology; Internal medicine; Psychology; Psychiatry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006706039,0.00009139411,0.0002470614,0.0003578918,0.000100165,0.00003248323,0.00006894307,0.00001302851,0.0002770985],"category_scores_gemma":[0.0002209883,0.00007262436,0.00004758372,0.0003497763,0.00009879166,0.0001259864,0.0001610899,0.000913235,0.000002713976],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004413899,"about_ca_system_score_gemma":0.0001379626,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000970465,"about_ca_topic_score_gemma":7.953336e-7,"domain_scores_codex":[0.9983993,0.0002090236,0.0003497085,0.0001451221,0.0006698787,0.0002269525],"domain_scores_gemma":[0.9992814,0.0002068213,0.0001538778,0.00005498218,0.0001597877,0.0001431293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006590312,0.0001694307,0.9823983,0.00001956253,0.00007976397,0.003647743,0.0004437492,0.0000117109,0.006304855,0.00001092576,0.00004826882,0.006206708],"study_design_scores_gemma":[0.00623973,0.002424742,0.9826862,0.0001212323,0.0001502014,0.004992465,0.001574585,0.0003308981,0.0003199562,0.0001287817,0.0009519993,0.00007923324],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938754,0.0003021297,0.00004926288,0.00457424,0.00004372193,0.0001921997,0.000004661885,0.000006632267,0.0009517581],"genre_scores_gemma":[0.9989243,0.00006526279,0.0001775634,0.0005851997,0.00006787511,0.000004963352,0.00000396147,0.00001700532,0.0001538736],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006127475,"threshold_uncertainty_score":0.3967602,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01585760554495875,"score_gpt":0.3050963753570647,"score_spread":0.289238769812106,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}