{"id":"W4297094034","doi":"10.1097/ppo.0000000000000618","title":"PI3K Inhibition for Squamous Cell Head and Neck Carcinoma","year":2022,"lang":"en","type":"article","venue":"The Cancer Journal","topic":"Ear and Head Tumors","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Head and neck; PI3K/AKT/mTOR pathway; Head and neck squamous-cell carcinoma; Medicine; Basal cell; Paclitaxel; Oncology; Cell; Cancer research; Phosphoinositide 3-kinase; Internal medicine; Head and neck cancer; Chemotherapy; Cancer; Biology; Surgery; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002443124,0.00005344099,0.0001016103,0.00003501987,0.0004371496,0.00001555444,0.00003936959,0.00001204136,0.0005066483],"category_scores_gemma":[0.00000925761,0.0000363227,0.00005070797,0.00005378991,0.00002551657,0.00002662511,0.00002884768,0.000316548,0.000001823657],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000115833,"about_ca_system_score_gemma":0.0001354654,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006313133,"about_ca_topic_score_gemma":0.00002134374,"domain_scores_codex":[0.999497,0.00003026688,0.0001123311,0.00007463692,0.0001403824,0.0001453849],"domain_scores_gemma":[0.9997185,0.00002832265,0.00005591281,0.00007748523,0.00003915175,0.00008058792],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005834163,0.0006454355,0.4516557,0.0007493194,0.0001047255,0.0006629219,0.01730014,0.0008209312,0.06084723,0.001384753,0.4291328,0.0308619],"study_design_scores_gemma":[0.02795421,0.007055269,0.7023852,0.0001678848,0.000756496,0.01250667,0.006490431,0.00216601,0.02223177,0.01071469,0.2069968,0.0005744751],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890882,0.003223924,0.00005432906,0.006025671,0.0002184281,0.0001877519,0.00001756807,0.000008003311,0.001176058],"genre_scores_gemma":[0.9963396,0.00006856353,0.00006942195,0.001686078,0.0006398452,0.00003436639,0.000003591659,0.00001295142,0.001145582],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2507296,"threshold_uncertainty_score":0.5547444,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02734176938778824,"score_gpt":0.2972157099185799,"score_spread":0.2698739405307916,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}