{"id":"W4297094034","doi":"10.1097/ppo.0000000000000618","title":"PI3K Inhibition for Squamous Cell Head and Neck Carcinoma","year":2022,"lang":"en","type":"article","venue":"The Cancer Journal","topic":"Ear and Head Tumors","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Head and neck; PI3K/AKT/mTOR pathway; Head and neck squamous-cell carcinoma; Medicine; Basal cell; Paclitaxel; Oncology; Cell; Cancer research; Phosphoinositide 3-kinase; Internal medicine; Head and neck cancer; Chemotherapy; Cancer; Biology; Surgery; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002436997,0.0003038357,0.0003528995,0.0002760689,0.0003151523,0.0004078224,0.0002265341,0.0002906401,0.006061675],"category_scores_gemma":[0.0001713129,0.00005899443,0.0005593744,0.0003765323,0.0001325089,0.0002462739,0.0002204997,0.000778525,0.001188295],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001049957,"about_ca_system_score_gemma":0.000988782,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001688091,"about_ca_topic_score_gemma":0.00669236,"domain_scores_codex":[0.9999267,0.000006755998,0.000006906905,0.000008469396,0.00002675264,0.00002450028],"domain_scores_gemma":[0.9999595,0.000005877305,0.000005837633,0.00000397722,0.000010412,0.00001447886],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01022313,0.00105641,0.004997697,0.001760538,0.0003391479,0.0007613826,0.00006717598,0.0009209181,0.0715277,0.001396648,0.04339319,0.8635561],"study_design_scores_gemma":[0.01699161,0.02822694,0.1358322,0.001286148,0.001927276,0.01353836,0.0002974393,0.005107033,0.2024301,0.005846883,0.5884166,0.0000994463],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6329826,0.2798505,0.002975147,0.01099214,0.001957738,0.000788813,0.003076807,0.0007943632,0.06658195],"genre_scores_gemma":[0.932368,0.04921095,0.00159475,0.002101848,0.000310192,0.0001783151,0.00201012,0.00003911616,0.01218668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006061675,"threshold_uncertainty_score":0.02027833,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02734176938778824,"score_gpt":0.2972157099185799,"score_spread":0.2698739405307916,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}