{"id":"W4297102193","doi":"10.1002/cbdv.202200202","title":"Copper‐Curcumin‐Bipyridine Dicarboxylate Complexes as Anticancer Candidates","year":2022,"lang":"en","type":"article","venue":"Chemistry & Biodiversity","topic":"Metal complexes synthesis and properties","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Northern British Columbia","funders":"Isfahan University of Medical Sciences","keywords":"Cytotoxicity; Chemistry; Curcumin; Reactive oxygen species; In vitro; Cell culture; Carboplatin; Dichlorofluorescein; Copper; Cisplatin; Biochemistry; Nuclear chemistry; Organic chemistry; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001625888,0.0001899418,0.0003613046,0.00002987101,0.0005889882,0.00002553118,0.0002542794,0.00004665519,0.01309544],"category_scores_gemma":[0.00005955741,0.0001726973,0.0001604569,0.0001691274,0.0002418017,0.00004765869,0.0004739692,0.0002726483,0.0001981581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001449947,"about_ca_system_score_gemma":0.000110816,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004496727,"about_ca_topic_score_gemma":0.000001944971,"domain_scores_codex":[0.9987128,0.00003718845,0.0001733543,0.0003690482,0.000415802,0.0002917459],"domain_scores_gemma":[0.9992592,0.00003787576,0.00008640243,0.0003667226,0.00006120667,0.0001885932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005874824,0.0001578291,0.06627272,0.0001672717,0.0001466961,0.00009632706,0.000192024,0.000003640313,0.8998709,0.000009853832,0.03219612,0.0002990966],"study_design_scores_gemma":[0.001019341,0.0001647509,0.007894995,0.00002674082,0.000232563,0.0001844753,0.0006777519,0.0000897546,0.7566824,0.00005239333,0.23265,0.0003247683],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9813479,0.00102996,0.000001374167,0.001524107,0.0001040773,0.0001468429,0.0003098052,0.00009425574,0.01544167],"genre_scores_gemma":[0.995114,0.00006922641,0.00007268675,0.0007407635,0.00008255145,0.000009512763,0.0002184381,0.000008515602,0.003684298],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2004539,"threshold_uncertainty_score":0.9878067,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02653940603716702,"score_gpt":0.2394000023360943,"score_spread":0.2128605962989273,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}