{"id":"W4297150762","doi":"10.3390/curroncol29100545","title":"Decreased FOXO1 Expression Is Correlated with Poor Prognosis in Myelodysplastic Syndromes","year":2022,"lang":"en","type":"article","venue":"Current Oncology","topic":"FOXO transcription factor regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Natural Science Foundation of China","keywords":"FOXO1; Myelodysplastic syndromes; Medicine; Immune system; Oncology; Cancer research; Gene expression profiling; Bioinformatics; Biology; Immunology; Internal medicine; Gene; Gene expression; Transcription factor; Genetics; Bone marrow","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001194242,0.0001507365,0.0001736743,0.0001177248,0.0001073291,0.000008491668,0.0001532947,0.0001005087,0.0003372272],"category_scores_gemma":[0.00002842288,0.0001408204,0.00005176567,0.0002015334,0.00006987456,0.000005529171,0.00008485137,0.0002107301,0.00001050691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001171222,"about_ca_system_score_gemma":0.0001645292,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008782949,"about_ca_topic_score_gemma":0.0000239523,"domain_scores_codex":[0.9987891,0.0001818124,0.0002233309,0.0003856736,0.0001803511,0.0002397635],"domain_scores_gemma":[0.9996005,0.00001755612,0.000104627,0.0001480127,0.00005040681,0.00007891544],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002317389,0.002116765,0.2639024,0.0000929015,0.00006776147,0.00006034367,0.0006258558,0.001573433,0.6954689,0.00007088803,0.01250826,0.02119512],"study_design_scores_gemma":[0.01169315,0.007791806,0.1608063,0.0001527376,0.0001490891,0.0004690901,0.0008048157,0.003370827,0.1138883,0.0001062792,0.6997108,0.001056803],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971489,0.0008740566,0.0006057585,0.000200351,0.0005525238,0.0003928968,0.0000394546,0.00002522129,0.0001608349],"genre_scores_gemma":[0.9987639,0.00004167571,0.0001708706,0.00008009603,0.00003659116,0.0002798573,0.0004924013,0.00002164166,0.0001129182],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6872026,"threshold_uncertainty_score":0.5742491,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04254503628042056,"score_gpt":0.3158102525116676,"score_spread":0.2732652162312471,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}