{"id":"W4297225789","doi":"10.14218/jctp.2022.00017","title":"Immune Checkpoint Inhibitor-Induced Hepatic Injury: A Clinicopathologic Review","year":2022,"lang":"en","type":"review","venue":"Journal of Clinical and Translational Pathology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"National Cancer Institute; National Institutes of Health","keywords":"Medicine; Differential diagnosis; Immune system; Autoantibody; Liver injury; Medical diagnosis; Gastrointestinal tract; Pathology; Immunology; Internal medicine; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003651087,0.0007785615,0.001113573,0.003569334,0.0003204104,0.000782731,0.0007570703,0.0006484461,0.002408096],"category_scores_gemma":[0.0008706971,0.0002627972,0.0005478301,0.003423605,0.0004122625,0.001157444,0.0005022618,0.0009751354,0.001012266],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004423302,"about_ca_system_score_gemma":0.001047372,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008664601,"about_ca_topic_score_gemma":0.001397894,"domain_scores_codex":[0.9998059,0.00002784957,0.00005682331,0.00003658516,0.00005489267,0.00001794728],"domain_scores_gemma":[0.9996068,0.0001802425,0.00008901536,0.00001162478,0.00008704268,0.00002531521],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008239609,0.00007260911,0.001149101,0.03247257,0.0001548678,0.00197225,0.0001159969,0.00040924,0.001317278,0.001671552,0.04026264,0.9203195],"study_design_scores_gemma":[0.00002831847,0.0001635867,0.006005079,0.0210421,0.0005208492,0.04554949,0.0002298942,0.0002603132,0.0007728885,0.002380686,0.9229915,0.0000553237],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002640789,0.9983487,0.000124596,0.0002219894,0.0001695794,0.000007129484,0.00002550543,0.000008948801,0.0008294948],"genre_scores_gemma":[0.001453834,0.9977602,0.0001668141,0.000165268,0.0001976875,0.000005884126,0.00004134758,0.000001652714,0.000207423],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003569334,"threshold_uncertainty_score":0.008055866,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1686837602474323,"score_gpt":0.4593350997922563,"score_spread":0.290651339544824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}