{"id":"W4297256589","doi":"10.1007/s10120-022-01336-3","title":"PD-L1 IHC testing: issues with interchangeability evidence based on laboratory-developed assays of unknown analytical performance","year":2022,"lang":"en","type":"letter","venue":"Gastric Cancer","topic":"Medical Imaging Techniques and Applications","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Royal University Hospital; University of Saskatchewan","funders":"","keywords":"Interchangeability; Medicine; Medical physics; Surgical oncology; Abdominal surgery; Computational biology; Internal medicine; Computer science; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005792258,0.0003367952,0.0006774509,0.0002606509,0.00008676651,0.00001796312,0.0003677665,0.0002316435,0.00226599],"category_scores_gemma":[0.0008558992,0.0002558705,0.0001078691,0.001523539,0.0003280026,0.00006062495,0.0001196514,0.002073199,0.000008545184],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005754986,"about_ca_system_score_gemma":0.001319273,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003304928,"about_ca_topic_score_gemma":0.000005345511,"domain_scores_codex":[0.9973081,0.0001153161,0.0004783382,0.000654955,0.001040137,0.0004031842],"domain_scores_gemma":[0.9975395,0.0005378678,0.000297021,0.0009066921,0.0005732717,0.0001456246],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000229595,0.0001322503,0.01573949,0.001087501,0.00005977992,0.00007644296,0.00002879279,0.00002398798,0.00009758845,0.000006840623,0.9758541,0.006663599],"study_design_scores_gemma":[0.0005430013,0.001491556,0.007718932,0.004006342,0.0004551914,0.00002485872,0.000009015374,0.01296814,0.0004489414,0.000008655395,0.9719625,0.0003628779],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.01648437,0.0006497296,0.002189435,0.9767385,0.0001888021,0.001614161,0.000294613,0.0003552504,0.001485109],"genre_scores_gemma":[0.1293117,0.001281675,0.0672804,0.7852884,0.004636661,0.004055532,0.0006158152,0.0002851152,0.007244706],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1914501,"threshold_uncertainty_score":0.9999893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1119686056717261,"score_gpt":0.3609194191215718,"score_spread":0.2489508134498457,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}