{"id":"W4297256589","doi":"10.1007/s10120-022-01336-3","title":"PD-L1 IHC testing: issues with interchangeability evidence based on laboratory-developed assays of unknown analytical performance","year":2022,"lang":"en","type":"letter","venue":"Gastric Cancer","topic":"Medical Imaging Techniques and Applications","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Royal University Hospital; University of Saskatchewan","funders":"","keywords":"Interchangeability; Medicine; Medical physics; Surgical oncology; Abdominal surgery; Computational biology; Internal medicine; Computer science; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.1242699,0.0008526987,0.00283552,0.002848392,0.003524211,0.008746244,0.005664429,0.05317878,0.002614866],"category_scores_gemma":[0.2801953,0.001411773,0.002724472,0.003120228,0.01247033,0.007762611,0.004402719,0.04288582,0.002759182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.009518866,"about_ca_system_score_gemma":0.007797658,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005191552,"about_ca_topic_score_gemma":0.013172,"domain_scores_codex":[0.8808607,0.05941542,0.02212798,0.008099815,0.02566587,0.003830145],"domain_scores_gemma":[0.6188036,0.3189664,0.01281341,0.009576793,0.03431525,0.005524611],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004554754,0.000104624,0.009279645,0.0007087063,0.0002509738,0.007832538,0.001762009,0.0004188675,0.001295437,0.03901464,0.8382522,0.1006248],"study_design_scores_gemma":[0.0004967349,0.0003225854,0.007699852,0.004179139,0.0004180634,0.01420232,0.002399247,0.003073349,0.002624189,0.1059482,0.8583477,0.000288702],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0009813523,0.002434911,0.001368788,0.9853126,0.006773061,0.00002195537,0.00008308225,0.00003301312,0.002991242],"genre_scores_gemma":[0.01748969,0.001616197,0.003894586,0.9514137,0.02429996,0.00006907786,0.00007322523,0.00005214365,0.001091385],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.8757302,"threshold_uncertainty_score":0.6572097,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1119686056717261,"score_gpt":0.3609194191215718,"score_spread":0.2489508134498457,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}