{"id":"W4297266708","doi":"10.1002/cpz1.563","title":"Using the HepaCometChip Assay for Broad‐Spectrum DNA Damage Analysis","year":2022,"lang":"en","type":"article","venue":"Current Protocols","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute for Liberal Studies; National Institute of Environmental Health Sciences","keywords":"DNA damage; Comet assay; DNA repair; Genotoxicity; DNA; Xenobiotic; Carcinogen; DNA adduct; Computational biology; Biology; Chemistry; Biochemistry; Cell biology; Enzyme; Toxicity","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002079331,0.001614495,0.0009496975,0.003219432,0.000702722,0.001215538,0.001215857,0.001770426,0.007617813],"category_scores_gemma":[0.002743742,0.0007719388,0.0009743375,0.001861825,0.0006914585,0.001064904,0.001212624,0.002275337,0.006725209],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004758405,"about_ca_system_score_gemma":0.0008304917,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007690591,"about_ca_topic_score_gemma":0.002994412,"domain_scores_codex":[0.9956236,0.0009481529,0.0003119638,0.001060505,0.001823075,0.000232768],"domain_scores_gemma":[0.9974695,0.0007222699,0.0004306904,0.0003584962,0.0008150955,0.0002039061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001606187,0.0001484409,0.001956315,0.0005068787,0.0001143427,0.0001266489,0.00009515315,0.0003791777,0.9639985,0.0009896259,0.003775758,0.02774843],"study_design_scores_gemma":[0.00004798086,0.0007009454,0.01009614,0.0001025369,0.0001579868,0.0007607852,0.00005532611,0.005123914,0.9379535,0.00101514,0.04389181,0.00009399519],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.07539824,0.004955749,0.881386,0.001132948,0.0007593769,0.001668261,0.008554808,0.009545798,0.01659879],"genre_scores_gemma":[0.1432262,0.007082315,0.7984236,0.002082308,0.0003170322,0.004586113,0.02049252,0.0008850247,0.02290483],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.007617813,"threshold_uncertainty_score":0.02548409,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07307976035528858,"score_gpt":0.3935882710340214,"score_spread":0.3205085106787329,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}