{"id":"W4297327203","doi":"10.1038/s42003-022-03963-z","title":"Multiscale neural gradients reflect transdiagnostic effects of major psychiatric conditions on cortical morphology","year":2022,"lang":"en","type":"article","venue":"Communications Biology","topic":"Functional Brain Connectivity Studies","field":"Neuroscience","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Centre Azrieli de recherche sur l'autisme, Institut et Hôpital Neurologiques de Montréal; NIH Blueprint for Neuroscience Research; Canadian Institutes of Health Research; National Institute of Biomedical Imaging and Bioengineering; National Institute on Aging; Natural Sciences and Engineering Research Council of Canada; Institute for Information and Communications Technology Promotion; National Research Foundation of Korea; Inha University; Medical Research Council; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; McDonnell Center for Systems Neuroscience; Ministry of Science and ICT, South Korea; Institute for Basic Science; National Institute of Mental Health; Hospital for Sick Children; Bundesministerium für Bildung und Forschung; Canada First Research Excellence Fund; Max-Planck-Gesellschaft; National Research Foundation; National Health and Medical Research Council; Norges Forskningsråd; National Institutes of Health; Canada Research Chairs; McGill University","keywords":"Morphology (biology); Neuroscience; Psychology; Brain morphometry; Biology; Medicine; Zoology; Magnetic resonance imaging","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009037339,0.0004180064,0.0003605833,0.001292665,0.0003557965,0.0005904872,0.0002232322,0.0002480257,0.001689823],"category_scores_gemma":[0.003254652,0.0001445186,0.0004753869,0.0008162032,0.0006318981,0.0003995424,0.00113511,0.0003148642,0.00007270068],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002919034,"about_ca_system_score_gemma":0.0002206116,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003604221,"about_ca_topic_score_gemma":0.008726774,"domain_scores_codex":[0.9995252,0.0001209217,0.00004579542,0.0001734124,0.00007514952,0.00005958518],"domain_scores_gemma":[0.9988777,0.0003519342,0.0004250698,0.0001856627,0.00009091302,0.0000687494],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008872683,0.00003983459,0.9153003,0.000210118,0.001384243,0.0005425407,0.001390115,0.001760802,0.04473354,0.00136974,0.0004595793,0.03192197],"study_design_scores_gemma":[0.000002738594,0.00004501907,0.9965353,0.000008101043,0.00007757072,0.0002989712,0.0002281677,0.0008038353,0.0009377075,0.0009295721,0.0001269948,0.000006054592],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959222,0.000266395,0.002814316,0.00005489366,0.000005635738,0.00001613475,0.0003335213,0.00001852945,0.0005684801],"genre_scores_gemma":[0.9990695,0.00004026047,0.0006915868,0.00001089831,0.000003416847,0.000007822928,0.0001227432,0.000006005213,0.0000477883],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003604221,"threshold_uncertainty_score":0.007166505,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0480456415131573,"score_gpt":0.3382107665319565,"score_spread":0.2901651250187992,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}