{"id":"W4297382897","doi":"10.3389/fimmu.2022.926895","title":"NLRP3: Role in ischemia/reperfusion injuries","year":2022,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"","keywords":"Inflammasome; Pyrin domain; Pattern recognition receptor; Immune system; Inflammation; Receptor; Reperfusion injury; Medicine; Pathogen; Ischemia; Innate immune system; Immunology; Cell biology; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003181023,0.0004468762,0.001207733,0.0005147557,0.00008488,0.00001501677,0.0007227032,0.0008322546,0.0001763841],"category_scores_gemma":[0.000140052,0.000463463,0.0003490945,0.0004041978,0.0001850529,0.000006497825,0.0007215302,0.0008460468,0.00001998531],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001475772,"about_ca_system_score_gemma":0.0003703812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000570336,"about_ca_topic_score_gemma":0.0000325456,"domain_scores_codex":[0.9975869,0.0003719157,0.0007238516,0.0006586893,0.0001046416,0.0005539681],"domain_scores_gemma":[0.9989581,0.00001846629,0.0002509964,0.000732944,0.00001615485,0.00002332075],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001159073,0.00011481,0.0004073411,0.0006604587,0.0002056311,0.0000190677,0.0001575217,0.000003541444,0.001211209,0.00002499975,0.0066542,0.9904253],"study_design_scores_gemma":[0.0004769292,0.0001743791,0.00001331904,0.0003243845,0.00004952793,0.00001764323,0.0004967056,0.000001520741,0.000722718,0.00007858713,0.997182,0.0004623191],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002991728,0.9921714,0.0000191537,0.00001314654,0.001535699,0.0004792276,0.00002243382,0.00001341677,0.002753795],"genre_scores_gemma":[0.00007501794,0.9964461,0.0003004275,0.00005802282,0.00007051892,0.000401212,0.001315841,0.00007409274,0.0012588],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9905277,"threshold_uncertainty_score":0.9997817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007855589630561644,"score_gpt":0.2494831036890678,"score_spread":0.2416275140585061,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}