{"id":"W4297458009","doi":"10.7554/elife.83135","title":"The SPARC complex defines RNAPII promoters in Trypanosoma brucei","year":2022,"lang":"en","type":"article","venue":"eLife","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Medical Research Council Canada; Wellcome Trust; Wellcome","keywords":"Trypanosoma brucei; Cell biology; Promoter; Biology; Genetics; Gene; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007149922,0.0001940162,0.0001847745,0.0003586554,0.0002277764,0.0003263396,0.0001094484,0.0001790703,0.0009250979],"category_scores_gemma":[0.0001867664,0.0002164097,0.0001358529,0.0002204665,0.000246272,0.0001175521,0.0002882679,0.0002064593,0.0004288297],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000476076,"about_ca_system_score_gemma":0.0002601475,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002758728,"about_ca_topic_score_gemma":0.006721617,"domain_scores_codex":[0.9998698,0.000008727469,0.00000736058,0.00004427671,0.00004175047,0.00002803384],"domain_scores_gemma":[0.9998832,0.0000178215,0.00003365739,0.00001248519,0.00002051596,0.00003242352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000562383,0.000002358245,0.001978374,0.00002512852,0.000003500516,0.0000378922,0.00003156259,0.00003494277,0.9969311,0.00005466681,0.00003889729,0.0008054412],"study_design_scores_gemma":[0.00001762031,0.0001080286,0.1754918,0.00002675411,0.0000288076,0.0007458683,0.0002431546,0.002048579,0.8158616,0.0002104243,0.005202404,0.00001498244],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940287,0.001662553,0.001981274,0.00005549406,0.00001007525,0.00001022351,0.0009123119,0.0000799305,0.001259486],"genre_scores_gemma":[0.9940401,0.0003896962,0.001768246,0.00005407146,0.000006108502,0.00001091979,0.002143316,0.00004045816,0.001547162],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002758728,"threshold_uncertainty_score":0.005485356,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04473452880007855,"score_gpt":0.3185334032483969,"score_spread":0.2737988744483184,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}