{"id":"W4297884240","doi":"10.21203/rs.3.rs-2058259/v1","title":"Integrated analysis of next generation sequencing minimal residual disease (MRD) and PET scan in transplant eligible myeloma patients","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Minimal residual disease; Residual; Multiple myeloma; Medicine; Oncology; Internal medicine; Computer science; Algorithm; Bone marrow","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006512897,0.0002940034,0.0005152556,0.0005389045,0.0002229659,0.001208005,0.0003060668,0.0005571423,0.002314329],"category_scores_gemma":[0.001873997,0.0002029411,0.0004941975,0.0004874748,0.0001265467,0.0002517377,0.0004045473,0.0004175997,0.0004939201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004354097,"about_ca_system_score_gemma":0.000446879,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002988684,"about_ca_topic_score_gemma":0.003436203,"domain_scores_codex":[0.9997621,0.00006857359,0.00001838913,0.00007363562,0.00003972787,0.00003764122],"domain_scores_gemma":[0.999476,0.0002433958,0.00007258745,0.00004184434,0.00009098049,0.0000751504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005716939,0.0002433153,0.8470809,0.0002210481,0.0005095613,0.001554875,0.0002729824,0.007065954,0.02070322,0.0007795242,0.006628506,0.1092232],"study_design_scores_gemma":[0.0002319606,0.0007792448,0.913587,0.0001613177,0.001245832,0.003464876,0.0007270567,0.04612529,0.01458385,0.004685143,0.0143344,0.0000740246],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9870595,0.002061626,0.002784812,0.000953414,0.00006997837,0.00003322738,0.004632309,0.0001493225,0.002255742],"genre_scores_gemma":[0.9917733,0.000462449,0.003189026,0.0003457583,0.00008446451,0.00002558109,0.003177831,0.00004907096,0.0008926452],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002988684,"threshold_uncertainty_score":0.007742226,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1298874402429994,"score_gpt":0.3920470768077536,"score_spread":0.2621596365647542,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}