{"id":"W4297960322","doi":"10.1093/jac/dkac313","title":"Paeoniflorin combined with norfloxacin ameliorates drug-resistant <i>Streptococcus suis</i> infection","year":2022,"lang":"en","type":"article","venue":"Journal of Antimicrobial Chemotherapy","topic":"Streptococcal Infections and Treatments","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"National Natural Science Foundation of China","keywords":"Paeoniflorin; Norfloxacin; Streptococcus suis; Biofilm; Microbiology; Efflux; Quorum sensing; Ciprofloxacin; Chemistry; Pharmacology; Antibiotics; Biology; Bacteria; Biochemistry; Gene; High-performance liquid chromatography; Virulence; Chromatography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001613366,0.000657133,0.0006024893,0.0003614773,0.0001237227,0.0002786219,0.0002407291,0.0003440756,0.001051027],"category_scores_gemma":[0.0001551116,0.0001173093,0.0003710354,0.0001198285,0.0002210135,0.0001729267,0.0001734871,0.0006944276,0.0002195301],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002027987,"about_ca_system_score_gemma":0.000260388,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008835092,"about_ca_topic_score_gemma":0.001140712,"domain_scores_codex":[0.99984,0.00002823162,0.00001789106,0.00001831972,0.00004708302,0.00004840644],"domain_scores_gemma":[0.9998636,0.00001478378,0.00004498566,0.000009534755,0.00002190593,0.00004521801],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001101269,0.0006293674,0.0004732265,0.0001855003,0.00002549475,0.00008391093,0.00002283581,0.0001163332,0.9859058,0.00003529298,0.0001340597,0.01128694],"study_design_scores_gemma":[0.0001868043,0.02488319,0.02522027,0.00006749454,0.0001988768,0.0007065543,0.00009013861,0.001798938,0.942468,0.00006141593,0.004301833,0.00001645102],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947989,0.002263627,0.001177888,0.0001433985,0.00005697621,0.00006648976,0.0001395288,0.0001486444,0.001204676],"genre_scores_gemma":[0.9951996,0.00146982,0.001301918,0.0001059514,0.00003088104,0.00004166339,0.0002874607,0.00001743084,0.001545398],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001051027,"threshold_uncertainty_score":0.003516078,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008525215373283488,"score_gpt":0.2435713966859112,"score_spread":0.2350461813126277,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}