{"id":"W4297964723","doi":"10.1007/7854_2022_392","title":"The Role of Dopamine D3 Receptors in Tobacco Use Disorder: A Synthesis of the Preclinical and Clinical Literature","year":2022,"lang":"en","type":"article","venue":"Current topics in behavioral neurosciences","topic":"Nicotinic Acetylcholine Receptors Study","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Nicotine; Dopamine; Dopaminergic; Dopamine receptor; Neuroscience; Dopamine receptor D3; Medicine; Drug; Psychology; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001063077,0.0005054332,0.001619041,0.002416808,0.0003091269,0.001135839,0.0007416462,0.0009940261,0.002563876],"category_scores_gemma":[0.001689166,0.0002282924,0.0006142966,0.002259266,0.0007453024,0.001169872,0.0004255802,0.001123268,0.0004600548],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007792294,"about_ca_system_score_gemma":0.001702239,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002260935,"about_ca_topic_score_gemma":0.005831468,"domain_scores_codex":[0.9998211,0.00003757795,0.00004958364,0.0000360792,0.00004123294,0.00001437582],"domain_scores_gemma":[0.9982558,0.001259998,0.0002047204,0.00003454584,0.0001918508,0.00005315177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.001080348,0.0002903541,0.007563801,0.03769674,0.0006704229,0.001777884,0.0002368766,0.0008681751,0.006485298,0.00669145,0.008118715,0.92852],"study_design_scores_gemma":[0.0003135573,0.003026114,0.09200247,0.05161082,0.007155243,0.01727069,0.001886104,0.001905534,0.006421184,0.0310925,0.7870762,0.0002396088],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001273808,0.9968584,0.000182558,0.0008766936,0.0001051863,0.000006313539,0.00005073471,0.000003736979,0.0006426102],"genre_scores_gemma":[0.007603063,0.9909553,0.0003292443,0.0003730542,0.0004981763,0.000007094471,0.00004498243,0.000001608532,0.0001874822],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002563876,"threshold_uncertainty_score":0.008576989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03492178541241318,"score_gpt":0.3555586301466235,"score_spread":0.3206368447342103,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}