{"id":"W4297976362","doi":"10.3389/fimmu.2022.1000681","title":"Combination treatment of radiofrequency ablation and peptide neoantigen vaccination: Promising modality for future cancer immunotherapy","year":2022,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Chinese Society of Clinical Oncology; Medical Science and Technology Project of Zhejiang Province; Science and Technology Program of Zhejiang Province; Health Commission of Zhejiang Province; Natural Science Foundation of Zhejiang Province; National Natural Science Foundation of China","keywords":"Medicine; Vaccination; Immunogenicity; Adjuvant; ELISPOT; Cancer; Immunotherapy; Cohort; Immune system; Internal medicine; Oncology; Immunology; Peptide vaccine; Antigen; T cell; Epitope","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003868347,0.0002843458,0.0006437915,0.0003205882,0.00008719738,0.0003618161,0.0003399654,0.0003533257,0.001591632],"category_scores_gemma":[0.0001549785,0.00008965086,0.0004784491,0.0001841259,0.0002143943,0.0004067692,0.0002972605,0.0007041291,0.0003134676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000174028,"about_ca_system_score_gemma":0.0002637403,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007832039,"about_ca_topic_score_gemma":0.0002531467,"domain_scores_codex":[0.9998612,0.00004362258,0.000006978114,0.00002823451,0.00003084143,0.0000289226],"domain_scores_gemma":[0.9999303,0.00001704513,0.00002154686,0.000007420676,0.000008635128,0.00001510126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00492712,0.00375433,0.007004853,0.00313355,0.0004374836,0.0006120107,0.0001197413,0.002604952,0.2958714,0.002338031,0.007233083,0.6719634],"study_design_scores_gemma":[0.0114376,0.1488734,0.08048299,0.002651195,0.003448078,0.01347921,0.0007094987,0.03323446,0.3199732,0.01574955,0.3696958,0.0002650257],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.6907953,0.2498984,0.04149427,0.004651959,0.001255343,0.001146767,0.0005759523,0.000426172,0.009755794],"genre_scores_gemma":[0.912222,0.06342314,0.01712365,0.001918797,0.0008191898,0.0008405877,0.0007206135,0.00003888521,0.002893217],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.001591632,"threshold_uncertainty_score":0.005324483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0133601970066196,"score_gpt":0.2786303492198491,"score_spread":0.2652701522132295,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}