{"id":"W4297989065","doi":"10.2147/opth.s362691","title":"Late-Onset Retinal Degeneration: Clinical Perspectives","year":2022,"lang":"en","type":"review","venue":"Clinical ophthalmology","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Eye Institute; University of California, San Diego; Research to Prevent Blindness","keywords":"Medicine; Macular degeneration; Degeneration (medical); Retinal degeneration; Ophthalmology; Dystrophy; Retinal pigment epithelium; Retinal; Atrophy; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002322774,0.000567043,0.001975124,0.0001014475,0.0002216763,0.00003520829,0.0008316154,0.001385134,0.002534071],"category_scores_gemma":[0.002280107,0.0005061228,0.001718164,0.0002269895,0.0006517859,0.00000384513,0.0007556138,0.001200585,0.0002762126],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003942278,"about_ca_system_score_gemma":0.001077542,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003169177,"about_ca_topic_score_gemma":0.000001492699,"domain_scores_codex":[0.9930736,0.002512608,0.002148548,0.00153707,0.0002291706,0.0004989873],"domain_scores_gemma":[0.9973497,0.0006836763,0.0007516026,0.0008672905,0.0000919271,0.0002557949],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006469583,0.001860728,0.02461445,0.001917621,0.001745185,0.001301548,0.00005249001,0.000002975329,0.000001460638,0.0003439456,0.0745667,0.8929459],"study_design_scores_gemma":[0.0004367581,0.001455206,0.0006720493,0.0001350226,0.0003100787,0.001333953,0.00005494447,0.000001083907,4.548654e-7,0.00008951934,0.9949262,0.0005847995],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.008445411,0.9794029,0.00001844588,0.0001008128,0.002147923,0.0005849586,0.00005000301,0.00002568168,0.009223888],"genre_scores_gemma":[0.0004553409,0.9877203,0.0006430091,0.0001770587,0.001546975,0.0001869837,0.001944922,0.00009012489,0.00723534],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9203594,"threshold_uncertainty_score":0.9999112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1642439645473838,"score_gpt":0.4670581508032448,"score_spread":0.302814186255861,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}