{"id":"W4297989065","doi":"10.2147/opth.s362691","title":"Late-Onset Retinal Degeneration: Clinical Perspectives","year":2022,"lang":"en","type":"review","venue":"Clinical ophthalmology","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Eye Institute; University of California, San Diego; Research to Prevent Blindness","keywords":"Medicine; Macular degeneration; Degeneration (medical); Retinal degeneration; Ophthalmology; Dystrophy; Retinal pigment epithelium; Retinal; Atrophy; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004233612,0.0008706884,0.001091825,0.002371014,0.0002931562,0.00114576,0.000712015,0.001102984,0.003883384],"category_scores_gemma":[0.0007644635,0.0001947663,0.0004177355,0.001681826,0.0004244017,0.001560819,0.0005452089,0.001927134,0.001875123],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004779001,"about_ca_system_score_gemma":0.0007400129,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007974858,"about_ca_topic_score_gemma":0.001330334,"domain_scores_codex":[0.999851,0.00002684029,0.00002619319,0.00002866216,0.00005031791,0.00001699519],"domain_scores_gemma":[0.9996465,0.0001664987,0.00003890153,0.00001036463,0.00009868644,0.0000390754],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001151499,0.0000724964,0.0004312827,0.01662026,0.00008285161,0.002592951,0.0001228104,0.0003448469,0.00220591,0.004947633,0.06351234,0.9089515],"study_design_scores_gemma":[0.00001960707,0.00007906346,0.001315122,0.008179164,0.0001191321,0.0171344,0.0001319777,0.00009527438,0.0003806569,0.003592951,0.9689258,0.00002669869],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001119098,0.9980057,0.00007700112,0.000375898,0.0002567358,0.000001869321,0.0000139229,0.00000616824,0.001150813],"genre_scores_gemma":[0.001092179,0.9974965,0.0001467804,0.0003473781,0.000446484,0.000003268204,0.00003303087,0.000001778496,0.0004326124],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003883384,"threshold_uncertainty_score":0.01299125,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1642439645473838,"score_gpt":0.4670581508032448,"score_spread":0.302814186255861,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}