{"id":"W4297997099","doi":"10.1182/blood.2022017560","title":"Lost in translation: cytoplasmic UBA1 and VEXAS syndrome","year":2022,"lang":"en","type":"letter","venue":"Blood","topic":"Otitis Media and Relapsing Polychondritis","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Translation (biology); Medicine; Genetics; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009152383,0.001379625,0.001421453,0.001062658,0.002304463,0.001858114,0.001356589,0.02684524,0.003349491],"category_scores_gemma":[0.009188443,0.0006684255,0.001264354,0.0009753519,0.002793449,0.002362003,0.001107316,0.01139969,0.001049482],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002745122,"about_ca_system_score_gemma":0.001181458,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002851342,"about_ca_topic_score_gemma":0.002155609,"domain_scores_codex":[0.9988304,0.0003240429,0.0001643774,0.0001725493,0.0002014808,0.0003071539],"domain_scores_gemma":[0.9968626,0.001909943,0.0003800704,0.0001211419,0.0002235733,0.000502732],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0002581815,0.00005066066,0.004873394,0.00007755602,0.00004659509,0.9504548,0.0002216534,0.0001264305,0.0009399905,0.003268689,0.03591425,0.003767736],"study_design_scores_gemma":[0.0004000621,0.000223206,0.007956129,0.0002500125,0.0001418922,0.9348953,0.0007151037,0.002162975,0.0009791045,0.008764688,0.04343797,0.00007363762],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"commentary","genre_gemma":"editorial","genre_scores_codex":[0.1268711,0.02157902,0.001866134,0.7842751,0.02351907,0.0001170677,0.0003783433,0.0001876948,0.04120652],"genre_scores_gemma":[0.6899569,0.00800722,0.001687886,0.1892855,0.0929662,0.0000991272,0.0001801712,0.000106843,0.01771004],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.02684524,"threshold_uncertainty_score":0.01991737,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01460980513551392,"score_gpt":0.2315632194828842,"score_spread":0.2169534143473703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}