{"id":"W4298002654","doi":"10.3390/v14102113","title":"Promiscuous Inflammasomes: The False Dichotomy of RNA/DNA Virus-Induced Inflammasome Activation and Pyroptosis","year":2022,"lang":"en","type":"review","venue":"Viruses","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research; Public Health Agency of Canada","keywords":"Pyroptosis; Inflammasome; AIM2; NLRC4; Biology; Innate immune system; Virus; Caspase 1; Cell biology; Virology; Immune system; Immunology; Inflammation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003899615,0.0005576664,0.0009518149,0.000197883,0.000274783,0.00006092501,0.0006131604,0.0003949795,0.0001312153],"category_scores_gemma":[0.0003040478,0.0003958933,0.0004206111,0.0003448588,0.0001899958,0.0000217256,0.0005450205,0.0004126433,0.00001334966],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003770282,"about_ca_system_score_gemma":0.0003519452,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009110295,"about_ca_topic_score_gemma":0.00002372768,"domain_scores_codex":[0.9976156,0.0003373031,0.0007974429,0.0005765382,0.00030577,0.0003673532],"domain_scores_gemma":[0.9981276,0.0001181838,0.000741131,0.000884861,0.00006459578,0.00006360732],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001029199,0.000110304,0.00004462191,0.003288346,0.0009024845,0.00000381464,0.0002246208,0.000002458429,0.1931268,0.0001101568,0.0005977818,0.8014857],"study_design_scores_gemma":[0.0003289903,0.0002469384,0.00002769233,0.0005022603,0.0003130225,0.000008494152,0.000128896,4.004953e-7,0.08276823,0.00002055797,0.915222,0.0004324664],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1022911,0.8954037,0.000004468675,0.00002224682,0.0001895241,0.001363742,0.00008550061,0.00002704628,0.0006126645],"genre_scores_gemma":[0.003235968,0.9951603,0.00001544471,0.0001502865,0.000212401,0.0006250144,0.0003298248,0.0001061148,0.0001646466],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9146243,"threshold_uncertainty_score":0.9998493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04337270821276203,"score_gpt":0.3030999458961236,"score_spread":0.2597272376833616,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}