{"id":"W4298056505","doi":"","title":"Potent, Selective, and Cell-active Chemical Probe of Protein Lysine Methyltransferases G9a and GLP: Cell-Based Assays","year":2010,"lang":"en","type":"preprint","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto; Structural Genomics Consortium","funders":"","keywords":"Methyltransferase; Lysine; Cell; Chemistry; Biochemistry; Cell biology; Biology; Amino acid; Methylation; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005879253,0.0007864892,0.0003727494,0.0003084998,0.0002523031,0.0005056809,0.00062075,0.001026786,0.002420696],"category_scores_gemma":[0.0002833912,0.0002534604,0.0003810152,0.0002890636,0.0005217114,0.0003641604,0.0006906109,0.0016196,0.0009172073],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004257358,"about_ca_system_score_gemma":0.0003152172,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003568789,"about_ca_topic_score_gemma":0.0008656614,"domain_scores_codex":[0.9997563,0.0000663791,0.00001054871,0.00005159778,0.00006495395,0.00005018596],"domain_scores_gemma":[0.9997943,0.00008516159,0.00002410253,0.00003693351,0.00002250229,0.00003706622],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001154243,0.00003323634,0.00008014707,0.00004541006,0.000007121942,0.00002634959,0.00002181358,0.0000869736,0.9974789,0.0003344663,0.0001237144,0.001646358],"study_design_scores_gemma":[0.00001367586,0.0001086763,0.0001598632,0.000001223992,0.000005322835,0.00003021144,0.000008760401,0.0001477685,0.9981389,0.00005516221,0.001327643,0.000002695016],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8444816,0.00715449,0.1293547,0.0009382162,0.0002757401,0.0003951752,0.002319373,0.0005975318,0.01448315],"genre_scores_gemma":[0.9497237,0.003782866,0.03265679,0.0002917829,0.00005377674,0.0002954057,0.001752502,0.0001054359,0.01133781],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002420696,"threshold_uncertainty_score":0.008098006,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005686699599714913,"score_gpt":0.2092064083150342,"score_spread":0.2035197087153193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}