{"id":"W4298086627","doi":"10.1161/circep.122.011514","title":"Targeting the RyR2 to Prevent Atrial Fibrillation","year":2022,"lang":"en","type":"letter","venue":"Circulation Arrhythmia and Electrophysiology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Heart Institute; Libin Cardiovascular Institute of Alberta","funders":"National Heart, Lung, and Blood Institute","keywords":"Atrial fibrillation; Ryanodine receptor 2; Cardiology; Medicine; Internal medicine; Receptor; Ryanodine receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009430615,0.000715577,0.001163178,0.0004908232,0.001759356,0.002203808,0.0006702135,0.03258905,0.004780539],"category_scores_gemma":[0.009020224,0.0004056646,0.001296003,0.0002591588,0.001559633,0.001236183,0.0007912905,0.025923,0.004114333],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00191265,"about_ca_system_score_gemma":0.001415745,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001668729,"about_ca_topic_score_gemma":0.003499326,"domain_scores_codex":[0.9991141,0.0002091745,0.000109439,0.0001344952,0.0002744891,0.0001582006],"domain_scores_gemma":[0.9979572,0.001277357,0.0001541679,0.00007658289,0.0001942562,0.0003403244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002993081,0.0001985236,0.00246976,0.0001686508,0.0001152679,0.01584976,0.0002394597,0.0003523295,0.002553224,0.01212486,0.9090548,0.05657398],"study_design_scores_gemma":[0.001130716,0.0006736025,0.004093103,0.0006011305,0.000195956,0.01805403,0.0003665184,0.002823191,0.002166818,0.03974542,0.9300323,0.0001172785],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"editorial","genre_scores_codex":[0.002145574,0.003572787,0.0004388602,0.961512,0.01801098,0.00003286947,0.00007609754,0.00007040222,0.01414042],"genre_scores_gemma":[0.02636335,0.003608606,0.0007687955,0.8751545,0.07616607,0.00009112123,0.00006229135,0.00004087996,0.01774434],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.03258905,"threshold_uncertainty_score":0.01599246,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00950620376694299,"score_gpt":0.2467650171296263,"score_spread":0.2372588133626833,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}