{"id":"W4298086627","doi":"10.1161/circep.122.011514","title":"Targeting the RyR2 to Prevent Atrial Fibrillation","year":2022,"lang":"en","type":"letter","venue":"Circulation Arrhythmia and Electrophysiology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Heart Institute; Libin Cardiovascular Institute of Alberta","funders":"National Heart, Lung, and Blood Institute","keywords":"Atrial fibrillation; Ryanodine receptor 2; Cardiology; Medicine; Internal medicine; Receptor; Ryanodine receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002146969,0.0004460834,0.0008332925,0.0002350556,0.0006758602,0.0000305905,0.0001097078,0.0006417696,0.0005388717],"category_scores_gemma":[0.0001921678,0.0003523431,0.0005110709,0.000408365,0.0001378369,0.00005590043,0.0001436567,0.002124648,0.00009120852],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002532119,"about_ca_system_score_gemma":0.0002572963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002028287,"about_ca_topic_score_gemma":5.523698e-7,"domain_scores_codex":[0.9969984,0.0005332095,0.0005214531,0.0008657096,0.0003403666,0.0007408808],"domain_scores_gemma":[0.9986022,0.0003486465,0.0002831201,0.0005489688,0.0001173223,0.0000997822],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002023021,0.00001406875,0.00009152552,0.0002941516,0.001183719,0.001310276,0.0004727611,0.0330444,0.1024975,0.0004883193,0.8417112,0.01686902],"study_design_scores_gemma":[0.000643703,0.001267086,0.00242687,0.00003155415,0.000457754,0.001882452,0.00001690447,0.001806931,0.0001522302,0.001557045,0.9892126,0.0005448812],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.3349013,0.003294056,0.0002674932,0.6572763,0.001425537,0.002313068,0.00003410739,0.0001934374,0.0002946067],"genre_scores_gemma":[0.4375818,0.001067876,0.0001968958,0.4839554,0.07170159,0.0001975862,0.003303391,0.0001917587,0.001803628],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1733209,"threshold_uncertainty_score":0.9998928,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00950620376694299,"score_gpt":0.2467650171296263,"score_spread":0.2372588133626833,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}