{"id":"W4298087864","doi":"10.1111/anae.15877","title":"Hypothesis‐generating procedures and unmasking novel associations in large observational studies: are we doing harm while doing good?","year":2022,"lang":"en","type":"letter","venue":"Anaesthesia","topic":"Climate Change and Health Impacts","field":"Environmental Science","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"B.C. Women's Hospital & Health Centre; St. Paul's Hospital; University of British Columbia","funders":"","keywords":"Medicine; Observational study; Harm; Intensive care medicine; Internal medicine; Social psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007454921,0.0003421232,0.0005021534,0.0001477497,0.0008403049,0.000103975,0.0002415633,0.0002727228,0.0005217415],"category_scores_gemma":[0.0001988243,0.000350607,0.00007227302,0.0004398853,0.00005691649,0.0002928686,0.0002946997,0.00097002,0.00002987732],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009806585,"about_ca_system_score_gemma":0.00007386385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002112898,"about_ca_topic_score_gemma":0.002051719,"domain_scores_codex":[0.9973552,0.0001205602,0.0005240612,0.0006132728,0.000614022,0.0007729203],"domain_scores_gemma":[0.9986897,0.0004402362,0.0005415762,0.0002269735,0.00001958608,0.00008194921],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000008503097,0.0001280116,0.2699194,0.0006361626,0.0000624305,0.0002630397,0.009726236,0.0009908398,0.0002535919,0.00006018556,0.7143751,0.003576529],"study_design_scores_gemma":[0.0005330998,0.00008559656,0.1072257,0.0007471804,0.00006010732,0.00002053744,0.002632893,0.0005890476,0.00001316354,0.0001609321,0.887248,0.0006836977],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.1860886,0.003311606,0.0000367623,0.8062223,0.0002729929,0.001107432,0.0005210508,0.0001364567,0.002302771],"genre_scores_gemma":[0.06454697,0.005646446,0.009866603,0.9156289,0.002042678,0.0005441706,0.0005536781,0.0002008371,0.0009697792],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.172873,"threshold_uncertainty_score":0.9998946,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1839944518697212,"score_gpt":0.335309215505437,"score_spread":0.1513147636357159,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}