{"id":"W4298352137","doi":"10.26443/msurj.v4i1.73","title":"Investigation of the role of heme oxygenase-1 in β-thalassemia pathophysiology","year":2009,"lang":"en","type":"article","venue":"McGill Science Undergraduate Research Journal","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; McGill University","funders":"","keywords":"Heme oxygenase; Heme; Globin; Thalassemia; Oxidative stress; Downregulation and upregulation; Hemoglobin; Pathophysiology; Chemistry; Cell; Biology; Molecular biology; Cell biology; Biochemistry; Gene; Endocrinology; Enzyme; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001895561,0.000135993,0.000117278,0.0001652562,0.0001147152,0.0002186144,0.0001703941,0.0002346585,0.0008976031],"category_scores_gemma":[0.000100113,0.00005488954,0.00006503158,0.0000857356,0.0001551398,0.0001599197,0.00007984011,0.0003085104,0.0001128623],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003270906,"about_ca_system_score_gemma":0.0002342385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005434059,"about_ca_topic_score_gemma":0.0005836121,"domain_scores_codex":[0.9999719,0.000007908733,0.00000160737,0.000005402533,0.000005686362,0.000007513475],"domain_scores_gemma":[0.9999436,0.00001419493,0.00001106535,0.000002950703,0.00001123563,0.00001696141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002267245,0.0001031463,0.002109726,0.0001086842,0.000006478787,0.0002677132,0.00005178324,0.0001126322,0.9834909,0.0009816911,0.0001575189,0.01238299],"study_design_scores_gemma":[0.00009979655,0.001917458,0.06401107,0.00006610218,0.00005864192,0.002501277,0.0002600211,0.003630687,0.9066759,0.001623759,0.01914004,0.00001524626],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9765588,0.01746377,0.002047803,0.001191677,0.00003927086,0.00003044835,0.00007074764,0.0000164781,0.002580997],"genre_scores_gemma":[0.9871987,0.007824673,0.002142771,0.0001396239,0.00002459204,0.00001775925,0.0000873929,0.000002538561,0.002561977],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008976031,"threshold_uncertainty_score":0.003002822,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02459233049624877,"score_gpt":0.3077899089952921,"score_spread":0.2831975784990434,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}