{"id":"W4299161187","doi":"10.17615/m864-xv86","title":"Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits","year":2020,"lang":"en","type":"article","venue":"UNC Libraries","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; Fonds de Recherche du Québec - Santé; Tartu Ülikool; Fondation Leducq; National Institutes of Health; Yoshida Scholarship Foundation; Queen Mary University of London; Canadian Institutes of Health Research; Donovan Family Foundation; Massachusetts General Hospital","keywords":"Genotyping; Biology; Exome sequencing; Exome; Genetics; Computational biology; Phenotype; Genotype; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003751555,0.0001796727,0.0003680422,0.00006264059,0.000132682,0.00006320511,0.00009253529,0.0001370697,0.0007982427],"category_scores_gemma":[0.0001990287,0.0001420958,0.00006685389,0.0003343939,0.0001172422,0.0002803493,0.00004950275,0.0002359853,0.00008120586],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001096138,"about_ca_system_score_gemma":0.000169028,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000052692,"about_ca_topic_score_gemma":0.000004916829,"domain_scores_codex":[0.9989281,0.00007178377,0.0002276016,0.0003211609,0.0001846608,0.0002666452],"domain_scores_gemma":[0.9994072,0.0000984797,0.0001068414,0.0001462605,0.00006332224,0.000177876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004019945,0.001085841,0.03576829,0.001021762,0.001685239,0.001289924,0.01802789,0.00008773591,0.8596767,0.02944694,0.04702725,0.000862475],"study_design_scores_gemma":[0.01849661,0.005572748,0.7933601,0.000538347,0.001490072,0.0001148133,0.001893729,0.0006450437,0.1503616,0.01302137,0.01327124,0.001234305],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9837613,0.0005847745,0.0006378802,0.004589984,0.0002645135,0.0003188423,0.0000239732,0.0004743653,0.009344356],"genre_scores_gemma":[0.9874884,0.00001732161,0.002703857,0.004866472,0.0003928886,0.00001136212,0.0001481799,0.0000433613,0.004328134],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7575918,"threshold_uncertainty_score":0.8740199,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02514981265692414,"score_gpt":0.2049052671208818,"score_spread":0.1797554544639577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}