{"id":"W4299161187","doi":"10.17615/m864-xv86","title":"Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits","year":2020,"lang":"en","type":"article","venue":"UNC Libraries","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; Fonds de Recherche du Québec - Santé; Tartu Ülikool; Fondation Leducq; National Institutes of Health; Yoshida Scholarship Foundation; Queen Mary University of London; Canadian Institutes of Health Research; Donovan Family Foundation; Massachusetts General Hospital","keywords":"Genotyping; Biology; Exome sequencing; Exome; Genetics; Computational biology; Phenotype; Genotype; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003932679,0.0008051659,0.001074379,0.001896176,0.0006869,0.001421279,0.0006780364,0.001001668,0.00479676],"category_scores_gemma":[0.007421003,0.0003564351,0.003059585,0.002775853,0.0003273995,0.0005560587,0.001183458,0.0007798973,0.0004512965],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000267822,"about_ca_system_score_gemma":0.0003711103,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002511184,"about_ca_topic_score_gemma":0.00528911,"domain_scores_codex":[0.996533,0.00134318,0.0003570657,0.001049684,0.0003641892,0.0003527133],"domain_scores_gemma":[0.9957116,0.002632152,0.0006975328,0.0006322759,0.000201267,0.0001251601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005795409,0.0001560655,0.8291565,0.002125545,0.06306133,0.001773993,0.0004557243,0.00313832,0.02631476,0.002260736,0.005964132,0.0597975],"study_design_scores_gemma":[0.0003510482,0.000593905,0.9178136,0.0004894246,0.04358254,0.002182217,0.0002530339,0.003822788,0.01019941,0.003212121,0.01741725,0.00008265588],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9363362,0.01921129,0.0170593,0.001270392,0.000266449,0.00007812137,0.02215558,0.000226075,0.003396594],"genre_scores_gemma":[0.9865689,0.002297685,0.004180284,0.0005130275,0.00007900373,0.00007595636,0.004692813,0.00008386758,0.001508489],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00479676,"threshold_uncertainty_score":0.02079827,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02514981265692414,"score_gpt":0.2049052671208818,"score_spread":0.1797554544639577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}