{"id":"W4299821623","doi":"10.17615/wgqy-mr91","title":"A genome-wide linkage study of autism spectrum disorder and the broad autism phenotype in extended pedigrees","year":2019,"lang":"en","type":"article","venue":"UNC Libraries","topic":"Autism Spectrum Disorder Research","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; National Institutes of Health; Wellcome Trust; GlaxoSmithKline; Canadian Institutes of Health Research; Autism Speaks","keywords":"Pedigree chart; Autism spectrum disorder; Linkage (software); Autism; Heritability of autism; Genetics; Phenotype; Broad spectrum; Genetic linkage; Genome; Biology; Computational biology; Psychology; Developmental psychology; Gene; Chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001305134,0.0004707133,0.0004669193,0.00150476,0.001017482,0.0004458298,0.0002897031,0.0002477955,0.001532702],"category_scores_gemma":[0.003331714,0.0002356179,0.0003090786,0.001622254,0.0004283332,0.0002077533,0.0009974531,0.0003865156,0.00009326672],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00070081,"about_ca_system_score_gemma":0.001152686,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.05529271,"about_ca_topic_score_gemma":0.07768762,"domain_scores_codex":[0.9991392,0.0004133795,0.00003467372,0.0002012327,0.0001254187,0.00008605694],"domain_scores_gemma":[0.9987726,0.0005319433,0.0002063405,0.0001552598,0.000122074,0.0002118343],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005826826,0.0001871101,0.9690553,0.0000299427,0.0004853387,0.005134215,0.002327688,0.001270494,0.005724843,0.0006286131,0.0003462551,0.01422753],"study_design_scores_gemma":[0.00007419218,0.000259901,0.9916441,0.00002342073,0.0002301201,0.003871015,0.000674147,0.001604486,0.0003640637,0.0003608107,0.0008763767,0.00001730178],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993248,0.00005266346,0.0003347805,0.00001672846,0.000001054172,0.000007817543,0.00009188071,0.000003376029,0.0001669307],"genre_scores_gemma":[0.9986429,0.00009021434,0.0009088358,0.00001342698,0.000002057166,0.00001122175,0.0002020159,0.00000210991,0.0001272493],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05529271,"threshold_uncertainty_score":0.1099418,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01571180194734275,"score_gpt":0.2482939254658623,"score_spread":0.2325821235185196,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}