{"id":"W4300006609","doi":"10.17615/d89j-9g85","title":"Significant locus and metabolic genetic correlations revealed in genome-wide association study of anorexia nervosa","year":2021,"lang":"en","type":"article","venue":"UNC Libraries","topic":"Eating Disorders and Behaviors","field":"Psychology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Instituto de Salud Carlos III; Korea Centers for Disease Control and Prevention; National Health and Medical Research Council; Medical Research Council; Canadian Institutes of Health Research; National Institutes of Health; Alexander von Humboldt-Stiftung; Schweizerische Anorexia Nervosa Stiftung; H. Lundbeck A/S; Regione del Veneto; Horizon 2020 Framework Programme; Vetenskapsrådet; Genesis Pharma; University of Toronto; Generalitat de Catalunya; China Scholarship Council; Bundesministerium für Bildung und Forschung; Bergens Forskningsstiftelse; Louis and Harold Price Foundation; Universitetet i Bergen; National Institute of Mental Health; Eesti Teadusagentuur; National Alliance for Research on Schizophrenia and Depression; National and Kapodistrian University of Athens; Centers for Disease Control and Prevention; Deutsche Forschungsgemeinschaft; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Flinders University; Government of Ontario; Institut National de la Santé et de la Recherche Médicale; Children's Hospital of Philadelphia; European Regional Development Fund; King's College London; NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research; Sanofi; South London and Maudsley NHS Foundation Trust; Bristol-Myers Squibb; Institut National de la Recherche Agronomique; Wellcome Trust; Lundbeckfonden; Eli Lilly and Company; Genome Canada; NHS Blood and Transplant; Agència de Gestió d'Ajuts Universitaris i de Recerca; National Institute for Health and Care Research; University of Otago; Norges Forskningsråd; Ministerstvo Zdravotnictví Ceské Republiky; AstraZeneca; EkstraStiftelsen Helse og Rehabilitering (Stiftelsen Dam); European Commission; Aarhus Universitet; GlaxoSmithKline; Pfizer; ZonMw","keywords":"Anorexia nervosa; Locus (genetics); Genome-wide association study; Association (psychology); Genetic association; Genetics; Psychology; Biology; Clinical psychology; Single-nucleotide polymorphism; Eating disorders; Gene; Genotype; Psychotherapist","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001175792,0.0001032955,0.0002562114,0.0001067367,0.00006570143,0.00004734684,0.00007372739,0.00009037455,0.0003293413],"category_scores_gemma":[0.0001666742,0.0001018267,0.00003058085,0.0004092466,0.00004164721,0.0001079943,0.00004994592,0.0001281929,0.00001039305],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001277193,"about_ca_system_score_gemma":0.000062115,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000341383,"about_ca_topic_score_gemma":0.000356581,"domain_scores_codex":[0.9988618,0.0002468968,0.0003406814,0.0002415622,0.0001356309,0.0001734404],"domain_scores_gemma":[0.9992008,0.0003258792,0.0001606891,0.000221817,0.00005428025,0.0000365867],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00001476903,0.000653387,0.9846104,0.000006412339,0.00005152608,0.0000236655,0.009099279,0.00003728624,0.0002375628,0.004311868,0.000476586,0.0004772881],"study_design_scores_gemma":[0.0008571778,0.0001242072,0.9882549,0.00000640929,0.00008112592,6.933249e-7,0.00686355,0.000005467557,0.0000270405,0.003362818,0.0003126836,0.0001039171],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952285,0.002434256,0.00005342758,0.0001961902,0.0001645221,0.000253866,0.0000103125,0.00002670553,0.001632271],"genre_scores_gemma":[0.9963254,0.00001534835,0.0008998495,0.00009661966,0.0000273334,0.00003411179,0.00002676261,0.00001505337,0.002559492],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003644539,"threshold_uncertainty_score":0.4152371,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01785835766058988,"score_gpt":0.2569807566497658,"score_spread":0.2391223989891759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}