{"id":"W4300006609","doi":"10.17615/d89j-9g85","title":"Significant locus and metabolic genetic correlations revealed in genome-wide association study of anorexia nervosa","year":2021,"lang":"en","type":"article","venue":"UNC Libraries","topic":"Eating Disorders and Behaviors","field":"Psychology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Instituto de Salud Carlos III; Korea Centers for Disease Control and Prevention; National Health and Medical Research Council; Medical Research Council; Canadian Institutes of Health Research; National Institutes of Health; Alexander von Humboldt-Stiftung; Schweizerische Anorexia Nervosa Stiftung; H. Lundbeck A/S; Regione del Veneto; Horizon 2020 Framework Programme; Vetenskapsrådet; Genesis Pharma; University of Toronto; Generalitat de Catalunya; China Scholarship Council; Bundesministerium für Bildung und Forschung; Bergens Forskningsstiftelse; Louis and Harold Price Foundation; Universitetet i Bergen; National Institute of Mental Health; Eesti Teadusagentuur; National Alliance for Research on Schizophrenia and Depression; National and Kapodistrian University of Athens; Centers for Disease Control and Prevention; Deutsche Forschungsgemeinschaft; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Flinders University; Government of Ontario; Institut National de la Santé et de la Recherche Médicale; Children's Hospital of Philadelphia; European Regional Development Fund; King's College London; NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research; Sanofi; South London and Maudsley NHS Foundation Trust; Bristol-Myers Squibb; Institut National de la Recherche Agronomique; Wellcome Trust; Lundbeckfonden; Eli Lilly and Company; Genome Canada; NHS Blood and Transplant; Agència de Gestió d'Ajuts Universitaris i de Recerca; National Institute for Health and Care Research; University of Otago; Norges Forskningsråd; Ministerstvo Zdravotnictví Ceské Republiky; AstraZeneca; EkstraStiftelsen Helse og Rehabilitering (Stiftelsen Dam); European Commission; Aarhus Universitet; GlaxoSmithKline; Pfizer; ZonMw","keywords":"Anorexia nervosa; Locus (genetics); Genome-wide association study; Association (psychology); Genetic association; Genetics; Psychology; Biology; Clinical psychology; Single-nucleotide polymorphism; Eating disorders; Gene; Genotype; Psychotherapist","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003361532,0.0004668874,0.0004477305,0.0008384239,0.0004560189,0.0007904442,0.0004272095,0.0005647535,0.001541025],"category_scores_gemma":[0.006495171,0.000366562,0.0009747884,0.001592517,0.0003773941,0.0001732267,0.0005606261,0.0006792826,0.0001260593],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001953304,"about_ca_system_score_gemma":0.0005069238,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002891967,"about_ca_topic_score_gemma":0.00443653,"domain_scores_codex":[0.9979614,0.0009107227,0.0001928668,0.000562326,0.000277341,0.00009541448],"domain_scores_gemma":[0.9970652,0.001411922,0.0008319385,0.0003268231,0.0002112438,0.0001528586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005455462,0.00003452092,0.9912691,0.00004758188,0.001720661,0.0003020218,0.00008379336,0.0003440003,0.003156707,0.00006451343,0.0001127716,0.002318886],"study_design_scores_gemma":[0.00005031503,0.00009718104,0.9972806,0.0000136177,0.0008532852,0.0004096767,0.0000436907,0.0005775864,0.0004054171,0.00008933462,0.0001724219,0.000006780607],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996933,0.0009718548,0.001218469,0.0001167339,0.00001941943,0.00001437055,0.000343601,0.00002763481,0.0003549428],"genre_scores_gemma":[0.9981633,0.0001657838,0.001227228,0.00003640845,0.00001394767,0.00001385685,0.0002562602,0.000007312051,0.0001159627],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003361532,"threshold_uncertainty_score":0.01777774,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01785835766058988,"score_gpt":0.2569807566497658,"score_spread":0.2391223989891759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}