{"id":"W4300117908","doi":"10.17615/zear-h193","title":"High Nucleosome Occupancy Is Encoded at Human Regulatory Sequences","year":2020,"lang":"en","type":"article","venue":"UNC Libraries","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Genome Canada; Ontario Genomics; Ontario Genomics Institute; Canadian Institute for Advanced Research; Howard Hughes Medical Institute","keywords":"Nucleosome; Occupancy; Computational biology; Genetics; Biology; Histone; Computer science; DNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001599189,0.0001981204,0.0002263595,0.0002270317,0.0002140277,0.0002580244,0.0001098934,0.0001834304,0.00201325],"category_scores_gemma":[0.0002987671,0.0001489222,0.0001265655,0.0002317545,0.0002189206,0.00008813391,0.0001951822,0.000188505,0.0006513895],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002006874,"about_ca_system_score_gemma":0.000255684,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00104015,"about_ca_topic_score_gemma":0.002522586,"domain_scores_codex":[0.9997993,0.00002563126,0.00001121827,0.00008188701,0.00005184703,0.00003012978],"domain_scores_gemma":[0.9998143,0.00005547492,0.00004572997,0.00002612822,0.0000247202,0.00003364323],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001033418,0.00001048182,0.004089697,0.00005711152,0.00001451885,0.00009141865,0.00002764655,0.0001240164,0.9867244,0.0004409011,0.000129255,0.008187224],"study_design_scores_gemma":[0.00000832053,0.0001384999,0.03682681,0.0000152305,0.00002680992,0.001197554,0.00003342838,0.000644126,0.9540161,0.0002932378,0.006788776,0.00001120306],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.970614,0.001740869,0.02103221,0.0000879648,0.00002631254,0.00001880643,0.001519148,0.0004399184,0.004520855],"genre_scores_gemma":[0.9901837,0.0003427966,0.006684354,0.00005381378,0.000005647545,0.000007563191,0.001100547,0.00002706655,0.001594533],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00201325,"threshold_uncertainty_score":0.006734967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0133320016040157,"score_gpt":0.2554093160489223,"score_spread":0.2420773144449066,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}