{"id":"W4300690741","doi":"10.1158/1078-0432.ccr-22-1389","title":"Associations between Pretreatment Body Composition Features and Clinical Outcomes among Patients with Metastatic Clear Cell Renal Cell Carcinoma Treated with Immune Checkpoint Blockade","year":2022,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"National Cancer Institute","keywords":"Renal cell carcinoma; Blockade; Medicine; Immune checkpoint; Oncology; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003174389,0.0001737826,0.0003033983,0.0003065203,0.0002194439,0.0002978585,0.0001615001,0.0002091797,0.0009581384],"category_scores_gemma":[0.0008241632,0.0001018902,0.0002358894,0.000434801,0.0002043198,0.0002217314,0.0002163449,0.0003671338,0.0001202427],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002758584,"about_ca_system_score_gemma":0.0002143522,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001170386,"about_ca_topic_score_gemma":0.002010173,"domain_scores_codex":[0.9997968,0.00004354176,0.00001844583,0.00005856072,0.00004836646,0.00003430458],"domain_scores_gemma":[0.9995241,0.00006337324,0.0002456181,0.00003790662,0.00004444871,0.00008457711],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005248578,0.00004552476,0.996249,0.000007419689,0.00005697808,0.00002596799,0.00001157815,0.00006549342,0.001423205,0.000006769673,0.00003768866,0.001545582],"study_design_scores_gemma":[0.000008959619,0.0001527841,0.9993049,0.000001633963,0.00002103633,0.00007864343,0.00002105447,0.0001874193,0.0001586358,0.000008520497,0.00005525125,0.000001184012],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995348,0.0001604528,0.00005973875,0.00001663103,0.000002011597,0.000003905916,0.0001229843,0.00000171935,0.00009765891],"genre_scores_gemma":[0.9996307,0.00003778365,0.00003821601,0.0000100822,0.000003904205,0.000004412899,0.0002236538,6.73721e-7,0.00005056353],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001170386,"threshold_uncertainty_score":0.003205299,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0864684432790599,"score_gpt":0.4085109312950261,"score_spread":0.3220424880159662,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}